|Table of Contents|

Research progress of exosomes in diagnosis and treatment of lung cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2022 04
Page:
731-736
Research Field:
Publishing date:

Info

Title:
Research progress of exosomes in diagnosis and treatment of lung cancer
Author(s):
CHENG Dazhao; TANG Xudong
Collaborative Innovation Center for Research and Development of Anti-tumor Active Substances，Guangdong Medical University，Guangdong Zhanjiang 524023，China．
Keywords:
liquid biopsy; exosome; lung cancer; biomarker; diagnosis; prognosis
PACS:
R734.2
DOI:
10.3969/j.issn.1672-4992.2022.04.038
Abstract:
Exosomes are extracellular vesicles with a diameter of 30~150 nm,which are secreted by a variety of cells including tumor cells,and mediate material transport and signal transmission between cells and tissues or between cells.In recent years,a large number of studies have shown that tumor-derived exosomes are involved in the occurrence and development of lung cancer and are closely related to the treatment of lung cancer.The miRNAs and proteins carried by exosomes are biomarkers for the diagnosis,prediction and prognosis of lung cancer.They can be used as raw materials for liquid biopsy of lung cancer.This article summarizes the research progress of exosomes in these aspects and their mechanisms in recent years,and provides references for the early diagnosis and treatment of lung cancer patients.

References:

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Memo

Memo:
National Natural Science Foundation of China(No.81372511）；国家自然科学基金面上项目（编号：81372511）;广东省基础与应用基础研究基金（编号：2019A1515011081）;广东省“扬帆计划”培养高层次人才项目（编号：201635011）
Last Update: 1900-01-01