|Table of Contents|

The expression of FoxM1 in malignant tumor and its role in tumorigenesis and development

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2022 04
Page:
728-731
Research Field:
Publishing date:

Info

Title:
The expression of FoxM1 in malignant tumor and its role in tumorigenesis and development
Author(s):
DONG Huan1; YIN Yifa2; DENG Fei2; HUANG Huazhong2
1.Department of Radiotherapy and Chemotherapy,No.2 People's Hospital of The Three Gorges University,Hubei Yichang 443000,China;2.Department of Radiotherapy and Chemotherapy,Yichang No.2 People's Hospital,Hubei Yichang 443000,China.
Keywords:
Forkhead Box M1; tumor; expression
PACS:
R730
DOI:
10.3969/j.issn.1672-4992.2022.04.037
Abstract:
In recent years,biomarkers have played an important role in the detection and treatment of cancer patients,and the search for new biomarkers has become a research hotspot.FoxM1 is a widely studied transcription factor,a large number of studies have found that FoxM1 is highly expressed in a variety of tumors compared with paracancerous tissues.The main function of FoxM1 is to regulate the transcriptional activation of factors involved in cell cycle transition to participate in the occurrence and development of tumors.However,the expression and the role of FoxM1 in malignant tumors have not been systematically elucidated,and the research on its specific mechanism and application as a tumor biomarker and therapeutic target is still in its infancy.Systematic elucidation of the expression and the role of FoxM1 in tumors may provide insights for predicting the prognosis of tumors and selecting new therapeutic targets.

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Memo:
湖北省自然科学基金资助项目（编号：2017CFB455）
Last Update: 1900-01-01