|Table of Contents|

Analysis on screening results of colorectal cancer among residents in Shanghai Baoshan area

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2022 01
Page:
134-139
Research Field:
LXBX
Publishing date:

Info

Title:
Analysis on screening results of colorectal cancer among residents in Shanghai Baoshan area
Author(s):
LI Nana; NI Xiangyun; MENG Xiangjun; ZHU Liming
Department of Gastroenterology，the Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200000,China.
Keywords:
colorectal cancer; precancerous lesions; screening
PACS:
R735.3+4
DOI:
10.3969/j.issn.1672-4992.2022.01.030
Abstract:
Objective:To analyze the results of colorectal cancer screening in Shanghai Baoshan area and explore the clinical significance of screening mode in diagnosis of colorectal cancer.Methods:The population who evaluated the positive result according to the community colorectal cancer screening and received colonoscopy examination from June 2017 to June 2019 in Shanghai Baoshan area,was enrolled.All of 769 cases were included.The population was divided into the normal group and the lesion group according to the results of colonoscopic diagnosis.The differences in gender and age between the two groups were analyzed.The lesion group was further divided into four groups according to the pathological results of colonoscopy:Colorectal cancer group,dysplasia group,adenoma group and benign polyp group.The differences in gender,age,lesion size,number and location were analyzed in those four groups.The benefits of risk assessment,FOBT testing,and parallel screening were also studied.Results:A total of 769 cases were included in this study,393 cases in the normal group and 376 cases in the lesion group,and the total lesion detection rate was 48.8%.The rate of colorectal cancer,dysplasia,adenoma,benign polyp detection was 1.6%,4.0%,32.1%,and 8.6%,respectively.There was statistically significant difference in the detection rate of lesions between different genders and ages(P＜0.05).There was statistically significant difference in the detection rate of benign polyps between different ages and in the size of the 12 cases of colorectal cancer(P＜0.05).There was statistically significant difference in size and location distribution of 247 cases of adenoma(P＜0.05),the lesion was mainly in left hemicolon with a diameter less than 1 cm.There was statistically significant difference in size,number,and location distribution of 66 cases of benign polyp(P＜0.05).The lesions were mainly in left hemicolon,multiple,and <1 cm in diameter.With colonoscopy as the gold standard,the sensitivity of primary screening(positive for either of the two) was 87.9%,higher than 79.2% of FOBT,and the false negative rate(12.0%) was lower than 20.8% of FOBT.Conclusion:The current community screening model of colorectal cancer in China can effectively improve the detection rate of colorectal cancer and precancerous lesions.Secondary prevention in the interventional stage of colorectal cancer may reduce its morbidity and mortality.

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Memo

Memo:
National Natural Science Foundation of China(No.81872419）；国家自然科学基金(编号：81872419)
Last Update: 2021-12-02