|Table of Contents|

Cost-effectiveness analysis of bortezomil,dexamethasone and thalidomide regimen in the treatment of multiple myeloma

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2020 04
Page:
622-625
Research Field:
Publishing date:

Info

Title:
Cost-effectiveness analysis of bortezomil,dexamethasone and thalidomide regimen in the treatment of multiple myeloma
Author(s):
Wang YangeLv GuoqingZhang YuanLiu XiankaiWu Sun
Department of Haematology,Xinxiang Medical University,Henan Xinxiang 453000,China.
Keywords:
bortezomidedexamethasonethalidomidemultiple myelomacost-effectiveness analysis
PACS:
R733.3
DOI:
10.3969/j.issn.1672-4992.2020.04.023
Abstract:
Objective:To investigate the short-term efficacy,safety and cost analysis of bortezomide,dexamethasone and thalidomide regimen(BDT) in the treatment of multiple myeloma(MM).Methods:40 patients with primary and refractory multiple myeloma treated in our hospital were treated with BDT regimen for 3 cycles.The curative effect,cost and adverse reaction were observed.Results:There were significant differences in the levels of M protein,β2-MG and hemoglobin in myeloma cells after treatment in 40 patients with MM(P<0.05).The total remission rate after treatment was 75.0%,of which 5 cases had complete remission,10 cases had very good partial remission,15 cases had partial remission,7 cases had stable disease and 3 cases had progressive disease.The cost-effect ratio of BDT regimen was 867.3 yuan,and the cost-effect ratio after sensitivity analysis was 310.4 yuan.Conclusion:Bortezomide,dexamethasone and thalidomide regimen have excellent efficacy,safety and moderate price in the treatment of multiple myeloma.

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Last Update: 2019-12-26