|Table of Contents|

Clinical application of minimally invasive ovarian pre-shift on young patients with advanced cervical cancer before radiotherapy

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2018 05
Page:
747-750
Research Field:
Publishing date:

Info

Title:
Clinical application of minimally invasive ovarian pre-shift on young patients with advanced cervical cancer before radiotherapy
Author(s):
Deng Yanli1Zhong Bangying1Huang Xiangyan2
1.Department of Obstetrics and Gynecology,the First Hospital of Laohekou,Hubei Laohekou 441800,China;2.Department of Obstetrics and Gynecology,the Cancer Hospital of Anyang City,Henan Anyang 455000,China.
Keywords:
ovarian transpositionchemoradiotherapyadvanced cervical cancerovarian function
PACS:
R737.33
DOI:
10.3969/j.issn.1672-4992.2018.05.024
Abstract:
Objective:To investigate the influence of minimally invasive ovarian pre-shift on sex hormone levels,ovarian function and survival rate of young patients with advanced cervical cancer by radiotherapy.Methods:110 young patients with advanced cervical cancer were chosen in the period from March 2010 to March 2016 in our hospital and randomly divided into two groups including control group (55 patients) with chemoradiotherapy used alone and observation group (55 patients) with minimally invasive ovarian pre-shift combined with chemoradiotherapy,and the levels of E2,FSH and LH before and after treatment,the Kupperman score after treatment,the influence of ovarian function,the survival rate and recurrence rate with follow-up of both groups were compared.Results:The levels of E2,FSH and LH before treatment of both groups were significant better than post-treatment (P<0.05).The levels of E2,FSH and LH after treatment of observation group were significant better than control group (P<0.05).The Kupperman score after treatment of control group was significant higher than observation group (P<0.05).The influence of ovarian function of observation group was significant higher than control group (P<0.05).There was no significant difference in the survival rate and recurrence rate between 2 groups (P>0.05).Conclusion:Minimally invasive ovarian pre-shift in the treatment of young patients with advanced cervical cancer by radiotherapy can efficiently regulate the sex hormone levels,relieve the menopause symptoms,protect ovarian function and not have negative impact on the survival time and recurrence risk.

References:

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