|Table of Contents|

The value of clinical indicators associated with cervical intraepithelial neoplasia for prediction of the treatment and prognosis of loop electrosurgical excision procedure

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2018 04
Page:
584-587
Research Field:
Publishing date:

Info

Title:
The value of clinical indicators associated with cervical intraepithelial neoplasia for prediction of the treatment and prognosis of loop electrosurgical excision procedure
Author(s):
Zhou DandanPan ShuhuiJi ZhongleiBian GanxiaLi Jiehua
Department of Obstetrics and Gynecology,Yancheng First People's Hospital,Jiangsu Yancheng 224000,China.
Keywords:
cervical intraepithelial neoplasiaclinical indicatorloop electrosurgical excision procedurepredictive value
PACS:
R737.33
DOI:
10.3969/j.issn.1672-4992.2018.04.025
Abstract:
Objective:To explore the value of clinical indicators associated with cervical intraepithelial neoplasia (CIN) for prediction of the treatment and prognosis of loop electrosurgical excision procedure (LEEP).Methods:418 cases of CIN Ⅱ-Ⅲ patients with LEEP surgery were collected from April 2012 to August 2014 in our hospital.The relationship of human papilloma virus (HPV),liquid based cytology test results,pathological examination results and the postoperative cut edge positive and CIN Ⅱ-Ⅲ recurrence were retrospectively analyzed.Results:Postoperative cut edge positive rate was 12.7% (53/418),and CIN Ⅲ and gland involvement group after LEEP had higher positive rate (P<0.05).There were 11 cases of recurrence (2.6%),and HPV16 positive patients after LEEP had higher postoperative recurrence rate (P<0.05).Logistic multifactor analysis showed that in preoperative CIN Ⅲ group postoperative cut edge positive probability increased 1.7 times.In preoperative disease inspection tired gland group postoperative cut edge positive probability increased 1.6 times.For preoperative HPV16 positive postoperative CIN Ⅱ-Ⅲ recurrence probability increased 5.7 times.Conclusion:Preoperative pathological examination such as CIN grade and gland involvement can predict LEEP operation effect.HPV16 positive can be used as an objective clinical indicators to predict postoperative CIN Ⅱ-Ⅲ recurrent.For CIN Ⅲ,gland involvement or HPV positive patients,intraoperative should take further attention,should be closely followed up postoperatively.

References:

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Last Update: 2017-12-29