|Table of Contents|

Influence of retroperitoneal laparoscopic operation for serum Ang,VEGF and T-lymphocyte subset in patients with renal carcinoma

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2018 01
Page:
65-68
Research Field:
Publishing date:

Info

Title:
Influence of retroperitoneal laparoscopic operation for serum Ang,VEGF and T-lymphocyte subset in patients with renal carcinoma
Author(s):
Zheng Yuanzhen1Chen Congqi1Wu Zhenfu1Wu Zhouyuan1Zhang Liyun1Lin Yunqiao1Zhang Yun1Li Zhiqiang1Chen Jintian1Lin Zhongying1Liu Qian
1.Department of Urology,Ningde Hospital Affiliated to Fujian Medical University,Fujian Ningde 352100,China;2.Department of Urology,General Hospital of Nanjing Military Region of Chinese People's Liberation Army,Jiangsu Nanjing 210002,China.
Keywords:
retroperitoneal laparoscopic operationrenal carcinomaangiotension (Ang)vascular endothelial growth factor (VEGF)T-lymphocyte subset
PACS:
R737.11
DOI:
10.3969/j.issn.1672-4992.2018.01.017
Abstract:
Objective:To investigate the influence of retroperitoneal laparoscopic operation for serum angiotension (Ang),vascular endothelial growth factor (VEGF) and T-lymphocyte subset in patients with renal carcinoma.Methods:90 patients with renal carcinoma were enrolled in this study.45 patients in observation group were treated by retroperitoneal laparoscopic operation and 45 patients in control group were treated by open radical nephrectomy.The general situations of operation and recovery were compared.The differences of serum Ang,VEGF and T-lymphocyte subset in two groups were observed.Results:The blood loss,time in bed and hospital stay of observation group were significantly less than those of control group (P<0.05).There were no significant differences in time of operation between two groups (P>0.05).The levels of serum Ang-1,Ang-2,VEGF in observation were significantly less,1 day and 5 day after operation,and were significantly lower than the same period in control group (P<0.05).The levels of CD3+,CD4+ and CD4+/CD8+ in observation group 1 day and 5 day after operation were significantly higher than those in control group (P<0.05).Conclusion:Compared with open radical nephrectomy,retroperitoneal laparoscopic operation has the advantages of less bleeding,rapid recovery.It can significantly reduce serum Ang,VEGF levels and decrease the effect on immune function and also be beneficial to recovery.

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Last Update: 2017-11-30