|Table of Contents|

Research progress of the relationship between Flot2 and malignant tumor

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2017 05
Page:
816-819
Research Field:
Publishing date:

Info

Title:
Research progress of the relationship between Flot2 and malignant tumor
Author(s):
Wang Fei1Wang Hongbing2
1.Xuzhou Medical University, Jiangsu Xuzhou 221002, China;2.Department of Oncology, Affiliated Hospital of Xuzhou Medical University, Jiangsu Xuzhou 221002, China.
Keywords:
Flot2lipid raftstumor invasion and metastasis
PACS:
R730.2
DOI:
10.3969/j.issn.1672-4992.2017.05.039
Abstract:
Lipid rafts are the microdomains of biological membrane that have vital biological functions.In recent years,more and more researches found that its characterized protein Flot2 was abnormally expressed in nasopharyngeal cancer,breast cancer,gastric cancer,renal cell carcinoma,malignant melanoma and other cancers.Moreover,in vivo and in vitro experiments showed that Flot2 was closely related with tumor proliferation,invasion and metastasis.In this paper,the structure and function of Flot2 gene and its relationship with malignant tumors were reviewed.

References:

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Last Update: 2017-01-26