|Table of Contents|

The clinical pathological significance of Hexokinase 2 expression in ovarian cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2017 01
Page:
123-126
Research Field:
Publishing date:

Info

Title:
The clinical pathological significance of Hexokinase 2 expression in ovarian cancer
Author(s):
Zhu XiaohuiLi FenZhang Shenhua
Department of Obstetrics and Gynecology,The First People's Hospital of Tianmen City,Hubei Tianmen 431700,China.
Keywords:
ovarian cancerHexokinase 2(HK-2)immunohistochemistryclinical significance
PACS:
R737.31
DOI:
10.3969/j.issn.1672-4992.2017.01.033
Abstract:
Objective:To explore the clinical pathological significance of Hexokinase 2(HK-2)expression in ovarian cancer.Methods:Immunohistochemistry was used to detect HK-2 expression in 68 cases of ovarian cancer tissue.Results:In 56 ovarian cancer patients HK-2 expression positive rate was 53.6%(30/56).High HK-2 expression was reltated with ovarian tumor staging(P=0.018),lymph node metastasis(P=0.035),but not related with age,differentiation,histology,and ascites.Conclusion:High HK-2 expression exist in ovarian cancer,MTDH may play an important role in tumor growth and development.Ttargeting HK-2 treatment may have important value for patients.

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Last Update: 2016-12-01