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Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:

2024 02

Page:

281-285

Research Field:

Publishing date:

Info

Title:

Clinicopathological analysis of collision tumor of rectal adenocarcinoma and neuroendocrine tumor

Author(s):

ZENG Yan; LI Li; WANG Yun

Department of Pathology,Guang'anmen Hospital,China Academy of Chinese Medical Sciences£¬Beijing 100053,China.

Keywords:

collision tumor; rectum; adenocarcinoma; neuroendocrine tumors

PACS:

R735.3

DOI:

10.3969/j.issn.1672-4992.2024.02.014

Abstract:

Objective:To analyze the clinicopathological and immunohistochemical characteristics of rectal collision tumor and hence to improve the level of diagnosis and differential diagnosis for the disease.Methods:We have selected 2 cases of rectal collision tumor in our department for the study£¬with 1 male and 1 female,and patients' age was 69 and 72 years old,respectively.Results:Upon retrospective analysis of their similar findings in other literature,the study showed that hematochezia,tenesmus,rectal mass and change in stool habits were the primary clinical symptoms.Microscopically,collision tumors constituted by moderately differentiated adenocarcinoma and neuroendocrine tumor(NET G1) located in the rectum.Immunohistochemically,the adenocarcinoma cells showed positive reactivity to MLH1,MSH2,MSH6 and PMS2,the NET cells showed positive reactivity to CD56,CgA and Syn.Conclusion:Collision tumor of rectal is a rare neoplasm and its clinical presentation is not very unique.Therefore,a high digree of clinical suspicion is required to avoid delays in diagnosis and treatment.

References:

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