|Table of Contents|

A case of low grade mucinous tumor of appendix diagnosed by ascites sediment embedding and literature review

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2024 02
Page:
285-288
Research Field:
Publishing date:

Info

Title:
A case of low grade mucinous tumor of appendix diagnosed by ascites sediment embedding and literature review
Author(s):
DING Chunxiao1; ZHANG Heng2; GUO Danyang2; ZHU Di2; WANG Jian2
1.Department of Pathology,Liaoning Province Chinese Medicine Research Institute,Liaoning Shenyang 110034,China；2.Department of Pathology,the First Affiliated Hospital of China Medical University,Liaoning Shenyang 110001,China.
Keywords:
mucous tumor of the appendix; cell sediment embedding; ascites
PACS:
R735.3+6
DOI:
10.3969/j.issn.1672-4992.2024.02.015
Abstract:
Objective:To explore the pathological and morphological characteristics of ascitic fluid exfoliated cells in low-grade appendiceal mucinous tumors,combining the pathological features of histological biopsy with clinical symptoms and signs to improve the understanding of the disease from a cytological perspective.Methods:Retrospective analysis of the clinical data,imaging features,ascitic fluid exfoliated cells,biopsy histopathological features,and prognosis of a patient with low-grade mucinous tumor of the appendix,and review relevant literature both domestically and internationally.Results:Low grade mucinous tumors of the appendix with ascites as the initial symptom are very rare.The main characteristic of their liquid based cell morphology is that the nucleus is usually small and regular,with only mild atypical changes.The cells are rich in mucus,and after sediment embedding and sectioning,the cells are columnar,polarized,single-layer or pseudostratified,and nuclear division is rare.This article reports a case of ascites accompanied by pelvic mass as the initial symptom for diagnosis.It is difficult to distinguish between imaging examination and primary ovarian tumor,and diagnosis must be based on the pathological morphological characteristics of exfoliated cells.Conclusion:The pathological characteristics of exfoliated cells in low-grade mucinous tumors of the appendix are mainly columnar in shape,with small and regular nuclei,small atypia,rare nuclear division,abundant mucus in the cells,and polarized cell arrangement.Ascites with pelvic masses are easily misdiagnosed as primary ovarian tumors on initial diagnosis.At the same time,it is very rare to diagnose low-grade mucinous tumors of the appendix through ascites sediment cytology.Therefore,it is necessary to combine cytological morphology,clinical symptoms and signs to improve understanding of the disease and achieve the goal of early diagnosis and treatment.

References:

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