|Table of Contents|

 Research status of cancer-associated fibroblasts in hepatocellular carcinoma

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2024 10
Page:
1949-1953
Research Field:
Publishing date:

Info

Title:
 Research status of cancer-associated fibroblasts in hepatocellular carcinoma
Author(s):
XUE Yi1234ZHAO Yongzhong1234CUI Yinxian1234ZHANG Min12345YANG Xiaojun12345
 
Keywords:
 cancer-associated fibroblastshepatocellular carcinomatumor microenvironment
PACS:
R735.7
DOI:
10.3969/j.issn.1672-4992.2024.10.034
Abstract:
 Hepatocellular carcinoma (HCC) is a highly aggressive malignancy with a poor prognosis.tumor microenvironment (TME) is a complex network that dynamically interacts with tumor cells through a large number of signaling mechanisms and pathways.Cancer-associated fibroblasts (CAFs) are the most important components of TME.They directly or indirectly play a role in promoting or suppressing cancer in HCC through angiogenesis,fibrosis,cell proliferation,immunosuppression and other aspects.This article reviews the research progress of CAFs and primary liver cancer.

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Memo

Memo:
 甘肃省卫生健康行业科研计划(编号:GSWSKY2020-45);国家卫健委胃肠肿瘤诊治重点实验室2022年度硕博士/博士后基金项目(编号:NHCDP2022001);甘肃省人民医院博士研究生导师培育项目(编号:22GSSYA-3);甘肃省基础研究创新群体项目(编号:22JR5RA709)
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