[1] SUNG H,FERLAY J,SIEGEL RL,et al.Global cancer statistics 2020:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J].CA:A Cancer Journal for Clinicians,2021,71(3):209-249.
[2] SIM YC,HWANG JH,AHN KM.Overall and disease-specific survival outcomes following primary surgery for oral squamous cell carcinoma:analysis of consecutive 67 patients[J].Journal of the Korean Association of Oral and Maxillofacial Surgeons,2019,45(2):83-90.
[3] PELTANOVA B,RAUDENSKA M,MASARIK M.Effect of tumor microenvironment on pathogenesis of the head and neck squamous cell carcinoma:a systematic review[J].Molecular Cancer,2019,18(1):63.
[4] MUGHEES M,SENGUPTA A,KHOWAL S,et al.Mechanism of tumour microenvironment in the progression and development of oral cancer[J].Molecular Biology Reports,2021,48(2):1773-1786.
[5] QIN Y,ZHENG X,GAO W,et al.Tumor microenvironment and immune-related therapies of head and neck squamous cell carcinoma[J].Molecular Therapy Oncolytics,2021,20:342-351.
[6] XIAO Y,YU D.Tumor microenvironment as a therapeutic target in cancer[J].Pharmacology & Therapeutics,2021,221:107753.
[7] LINDHOUT FW,CAO Y,KEVENAAR JT,et al.VAP-SCRN1 interaction regulates dynamic endoplasmic reticulum remodeling and presynaptic function[J].The EMBO Journal,2019,38(20):e101345.
[8] WAY G,MORRICE N,SMYTHE C,et al.Purification and identification of secernin,a novel cytosolic protein that regulates exocytosis in mast cells[J].Molecular Biology of the Cell,2002,13(9):3344-3354.
[9] STEPHENS DC,HARRIS DA.Organizing 《Elements》:Facilitating exocytosis and promoting metastasis[J].Trends in Cancer,2020,6(4):273-276.
[10] 朱元庆,樊军卫,伍雷,等.胞吐作用调节蛋白SCRN1在结肠癌中的表达及意义[J].中国现代普通外科进展,2013,16(06):432-437.
ZHU YQ,FAN JW,WU L,et al.Expression and significance of SCRN1 that regulate exocytosis in colon carcinoma[J].Chinese Journal of Current Advances in General Surgery,2013,16(06):432-437.
[11] 张玲,邹多武.生物信息学分析筛选胆管癌新候选基因及其意义[J].中国医学前沿杂志(电子版),2020,12(07):123-128.
ZHANG L,ZOU DW.Novel candidate genes in cholangiocarcinoma determined by intergrated bioinformatic analysis[J].Chinese Journal of the Frontiers of Medical Science(Electronic Version),2020,12(07):123-128.
[12] HE T,HUANG L,LI J,et al.Potential prognostic immune biomarkers of overall survival in ovarian cancer through comprehensive bioinformatics analysis:a novel artificial intelligence survival prediction system[J].Frontiers in Medicine,2021,8:587496.
[13] OKADA T,NAKAMURA M,NISHIKAWA J,et al.Identification of genes specifically methylated in Epstein-Barr virus-associated gastric carcinomas[J].Cancer Science,2013,104(10):1309-1314.
[14] MIYOSHI N,ISHII H,MIMORI K,et al.SCRN1 is a novel marker for prognosis in colorectal cancer[J].Journal of Surgical Oncology,2010,101(2):156-159.
[15] AKHTAR M,HAIDER A,RASHID S,et al.Paget's 《Seed and Soil》 theory of cancer metastasis:an idea whose time has come[J].Advances in Anatomic Pathology,2019,26(1):69-74.
[16] BIFFI G,TUVESON DA.Diversity and biology of cancer-associated fibroblasts[J].Physiological Reviews,2021,101(1):147-176.
[17] HU C,ZHANG Y,WU C,et al.Heterogeneity of cancer-associated fibroblasts in head and neck squamous cell carcinoma:opportunities and challenges[J].Cell Death Discovery,2023,9(1):124.
[18] DONG G,CHEN P,XU Y,et al.Cancer-associated fibroblasts:Key criminals of tumor pre-metastatic niche[J].Cancer Letters,2023,566:216234.
[19] GENG X,CHEN H,ZHAO L,et al.Cancer-associated fibroblast (CAF) heterogeneity and targeting therapy of CAFs in pancreatic cancer[J].Frontiers in Cell and Developmental Biology,2021,9:655152.
[20] BEDESCHI M,MARINO N,CAVASSI E,et al.Cancer-associated fibroblast:role in prostate cancer progression to metastatic disease and therapeutic resistance[J].Cells,2023,12(5):802.
[21]CARAMELO B,ZAGORAC S,CORRAL S,et al.Cancer-associated fibroblasts in bladder cancer:origin,biology,and therapeutic opportunities[J].European Urology Oncology,2023,6(4):366-375.
[22] AKKIZ H.Emerging role of cancer-associated fibroblasts in progression and treatment of hepatocellular carcinoma[J].International Journal of Molecular Sciences,2023,24(4):3941.
[23] ZHOU B,CHEN WL,WANG YY,et al.A role for cancer-associated fibroblasts in inducing the epithelial-to-mesenchymal transition in human tongue squamous cell carcinoma[J].Journal of Oral Pathology & Medicine,2014,43(8):585-592.
[24] 陆涛,王旭青.CAFs在胰腺癌肿瘤微环境中作用的研究进展[J].现代肿瘤医学,2023,31(01):177-182.
LU Tao,WANG Xuqing.Research progress of CAFs in the microenvironment of pancreatic cancer[J].Modern Oncology,2023,31(01):177-182.
[25] WANG D,TIAN M,FU Y,et al.Halofuginone inhibits tumor migration and invasion by affecting cancer-associated fibroblasts in oral squamous cell carcinoma[J].Frontiers in Pharmacology,2022,13:1056337.
[26] LI X,JIANG E,ZHAO H,et al.Glycometabolic reprogramming-mediated proangiogenic phenotype enhancement of cancer-associated fibroblasts in oral squamous cell carcinoma:role of PGC-1α/PFKFB3 axis[J].British Journal of Cancer,2022,127(3):449-461.
[27] 彭艳霜.SCRN1调控PI3K/AKT信号通路对口腔鳞状细胞癌侵袭、迁移的影响[D].南充:川北医学院,2021.
PENG YS.Effect of SCRN1 on invasion and migration of oral squamous cell carcinoma by regulating PI3K/AKT signaling pathway[D].Nanchong:North Sichuan Medical College,2021.
[28] NAGASE H,VISSE R,MURPHY G.Structure and function of matrix metalloproteinases and TIMPs[J].Cardiovascular Research,2006,69(3):562-573.
[29] HENRIET P,EMONARD H.Matrix metalloproteinase-2:Not (just) a "hero" of the past[J].Biochimie,2019,166:223-232.
[30] LIN S,JIANG T,YU Y,et al.Secernin-1 contributes to colon cancer progression through enhancing matrix metalloproteinase-2/9 exocytosis[J].Disease Markers,2015,2015:230703.