|Table of Contents|

m6A methylation modification of circRNA and its research progress in tumors

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2024 02
Page:
363-370
Research Field:
Publishing date:

Info

Title:
m6A methylation modification of circRNA and its research progress in tumors
Author(s):
HONG LihuiSHANG JinjingDONG YepingWANG HuiDU Lailing
Zhejiang Shuren University,Zhejiang Hangzhou 310000,China.
Keywords:
tumorcircular RNAN6-methyladenosineepigenetics
PACS:
R730
DOI:
10.3969/j.issn.1672-4992.2024.02.030
Abstract:
Circular RNA is a class of non-coding RNA widely found in organisms,with properties such as molecular structure stability,high conservation,and expression specificity.While N6-methyladenosine(m6A) is the most common modification in eukaryotic RNA.A lot of evidence suggests that circular RNA and m6A modifications play a crucial role in tumor development and progression.This paper describes the concept of circular RNA and m6A methylation modification and the connection with tumors,summarizes the tumor-related circular RNA with m6A modification,and discusses their application prospects in the clinical field,in order to provide new ideas for early diagnosis,clinical treatment and prognosis prediction of tumors.

References:

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Memo

Memo:
National Natural Science Foundation of China(No.81700241);国家自然科学基金(编号:81700241);浙江树人学院青年博士创新计划(编号:2019QC09);浙江树人学院一般科研项目(编号:2019A11001)
Last Update: 1900-01-01