|Table of Contents|

Clinical application of ECT bone imaging and bone marrow smear in bone metastasis of neuroblastoma

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2020 06
Page:
989-993
Research Field:
Publishing date:

Info

Title:
Clinical application of ECT bone imaging and bone marrow smear in bone metastasis of neuroblastoma
Author(s):
Zhang Shuping1Shen Leyuan2Song Yiling3Peng Xiongwen1Chen Yueqiong1
1.Department of Hematology;2.Department of Medical Examination Center;3Department of Laboratory,Sun Yat-sen University Cancer Center,Guangdong Guangzhou 510060,China.
Keywords:
neuroblastomabone marrow smearECT bone imagingbone metastasis
PACS:
R739.4
DOI:
10.3969/j.issn.1672-4992.2020.06.025
Abstract:
Objective:To investigate the clinical application value of ECT bone imaging and bone marrow smear in bone metastasis of neuroblastoma.Methods:We retrospectively analyzed the clinical data of 216 patients with neuroblastoma diagnosed by pathology,lymph node or bone marrow biopsy from October 2011 to October 2018,and collected their ECT bone imaging and bone marrow smear results in the same period,so that we could analyse the clinical application value of the two methods in bone metastasis of neuroblastoma.Results:Among the patients,106 cases were positive in ECT bone imaging,while 110 cases were negative results,and the positive rate was 49.07%.84 cases were positive in bone marrow smear,and 132 cases were negative results,and the positive rate was 38.89%.There were 46 cases with positive ECT bone imaging but negative for bone marrow smear,accounting for 21.30%.On the contrary,24 cases with negative ECT bone imaging but positive for bone marrow smear,accounted for 11.11%.There were 60 cases with both positive results and 86 cases with both negative results.The coincidence rate of the two methods in the diagnosis of bone metastases in patients with neuroblastoma was 67.59%.Among 106 cases of ECT bone imaging positive,60 cases were positive for bone marrow smear,and the positive rate of bone marrow metastasis was 56.60%,indicating that 56.60% of patients had bone marrow metastasis when ECT bone imaging showed bone metastasis.Conclusion:ECT bone imaging and bone marrow smear examination have important clinical significance in the clinical stage,efficacy and prognosis evaluation of bone metastasis in NB patients.It is recommended that ECT bone imaging and bone marrow smear should be performed simultaneously to improve the detection rate and accuracy in bone metastasis of neuroblastoma.

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Last Update: 2020-02-10