|Table of Contents|

Biological mechanism of anticancer activity of resveratrol

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2020 02
Page:
338-341
Research Field:
Publishing date:

Info

Title:
Biological mechanism of anticancer activity of resveratrol
Author(s):
Yang YanliCai ChanglanGu Yiming
Navy General Hospital,Beijing 100048,China.
Keywords:
resveratrolanticancerbiological mechanism
PACS:
R730.1
DOI:
10.3969/j.issn.1672-4992.2020.02.037
Abstract:
Resveratrol,a safe and multi-agent with benefical properties,natural polyphenolic phytoalexin,has atrracted much attention due to its wide biological effects,and plays an important role in human health,such as antioxidantion,anti-inflammatory,immune regulation,neuroprotection and so on.In particularly,resveratrol as a therapetutic prevention product is useful to treat and prevent varieties of cancer,but the mechnisam of anticancer is still not clear.Resveratrol has broad prospects as a preventive and therapeutic agent for cancer,underlying complicated structures and diverse bioloactivities.In this concise review,we highlight the role of resveratrol in the prevention and therapy of cancer.Also,we discuss the molecular mechnisams inculding cancer cells apoptosis,inbibition of P450,as chemotherapeutic agents,attenuation of COX-2,regulation cell cycle,suppression angiogenesis,down-regulation cytokine NF-κB and inducing autophagy and inhibtion cell migration.

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Last Update: 2019-11-29