［1］Testa U，Castelli G，Pelosi E.Esophageal cancer：Genomic and molecular characterization，stem cell compartment and clonal evolution［J］.Medicines，2017，4(3)：1-31.
［2］Basakran NS.CD44 as a potential diagnostic tumor marker［J］.Saudi Medical Journal，2015，36(3)：273-279.
［3］Senbanjo LT，Chellaiah MA.CD44：A multifunctional cell surface adhesion receptor is a regulator of progression and metastasis of cancer cells［J］.Front Cell Dev Biol，2017，5(Pt 3)：18.
［4］Marchetti L，Luin S，Bonsignore F，et al.Ligand-induced dynamics of neurotrophin receptors investigated by single-molecule imaging approaches［J］.International Journal of Molecular Sciences，2015，16(1)：1949-1979.
［5］Vilar M，Mira H.Regulation of neurogenesis by neurotrophins during adulthood：Expected and unexpected roles［J］.Frontiers in Neuroscience，2016，10(63)：26.
［6］Barker PA.p75NTR is positively promiscuous：Novel partners and new insights［J］.Neuron，2004，42(4)：529-533.
［7］Ranji P，Salmani KT，Saeedikhoo S，et al.Targeting cancer stem cell-specific markers and/or associated signaling pathways for overcoming cancer drug resistance［J］.Tumour Biology，2016，37(10)：1-17.
［8］Ko KS，Arora PD，Mcculloch CA.Cadherins mediate intercellular mechanical signaling in fibroblasts by activation of stretch-sensitive calcium-permeable channels［J］.Journal of Biological Chemistry，2001，276(38)：35967-3577.
［9］True LD，Zhang H，Ye M，et al.CD90/THY1 is overexpressed in prostate cancer-associated fibroblasts and could serve as a cancer biomarker［J］.Modern Pathology，2010，23(10)：1346-1356.
［10］Lu H，Clauser KR，Tam WL，et al.A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages［J］.Nature Cell Biology，2014，16(11)：1105-1117.
［11］Tang KH，Dai YD，Tong M，et al.A CD90 (+) tumor-initiating cell population with an aggressive signature and metastatic capacity in esophageal cancer［J］.Cancer Research，2013，73(7)：2322-2332.
［12］Medema JP.Cancer stem cells：The challenges ahead［J］.Nature Cell Biology，2013，15(4)：338-344.
［13］Fargeas CA，Joester A，Missolkolka E，et al.Identification of novel Prominin-1/CD133 splice variants with alternative C-termini and their expression in epididymis and testis［J］.Journal of Cell Science，2004，117(18)：4301-4311.
［14］Galizia G，Gemei M，Del VL，et al.Combined CD133/CD44 expression as a prognostic indicator of disease-free survival in patients with colorectal cancer［J］.Archives of Surgery，2012，147(1)：18-24.
［15］Sui YP，Jian XP，Ma LI，et al.Prognostic value of cancer stem cell marker CD133 expression in esophageal carcinoma：A Meta-analysis［J］.Molecular & Clinical Oncology，2016，4(1)：77-82.
［16］Doyle LA，Yang W，Abruzzo LV，et al.A multidrug resistance transporter from human MCF-7 breast cancer cells［J］.Proceedings of the National Academy of Sciences of the United States of America，1998，95(26)：15665-15670.
［17］Ueda K.ABC proteins protect the human body and maintain optimal health［J］.Journal of the Agricultural Chemical Society of Japan，2011，75(3)：401-409.
［18］Szepesi ，Matula Z，Szigeti A，et al.ABCG2 is a selectable marker for enhanced multilineage differentiation potential in periodontal ligament stem cells［J］.Stem Cells & Development，2015，24(2)：244-252.
［19］Shukla S，Meeran SM.Epigenetics of cancer stem cells：Pathways and therapeutics［J］.Biochimica Et Biophysica Acta，2014，1840(12)：3494-3502.
［20］Liu J，Gurpur PB，Kaufman SJ.Genetically determined proteolytic cleavage modulates alpha7 beta1 integrin function［J］.Journal of Biological Chemistry，2008，283(51)：35668-35678.
［21］Franceschi ND，Hamidi H，Alanko J，et al.Integrin traffic-the update［J］.Journal of Cell Science，2015，128(5)：839-852.
［22］Ming XY，Fu L，Zhang LY，et al.Integrin 7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma［J］.Nature Communications，2016，7：13568.
［23］Zhao JS，Li WJ，Ge D，et al.Tumor initiating cells in esophageal squamous cell carcinomas express high levels of CD44［J］.PLoS One，2011，6(6)：e21419.
［24］Huang SD，Yuan Y，Liu XH，et al.Self-renewal and chemotherapy resistance of p75NTR positive cells in esophageal squamous cell carcinomas［J］.Bmc Cancer，2009，9(1)：9.
［25］Tsai ST，Wang PJ，Liou NJ，et al.ICAM1 is a potential cancer stem cell marker of esophageal squamous cell carcinoma［J］.PLoS One，2015，10(11)：e0142834.
［26］Okumura T，Shimada Y，Imamura M，et al.Neurotrophin receptor p75(NTR) characterizes human esophageal keratinocyte stem cells in vitro［J］.Oncogene，2003，22(26)：4017-4026.
［27］Huang L，Lu Q，Han Y，et al.ABCG2/V-ATPase was associated with the drug resistance and tumor metastasis of esophageal squamous cancer cells［J］.Diagnostic Pathology，2012，7(1)：1-7.
［28］Zhang G，Ma L，Xie YK，et al.Esophageal cancer tumorspheres involve cancer stem-like populations，with elevated aldehyde dehydrogenase enzymatic activity［J］.Molecular Medicine Reports，2012，6(3)：519-524.
［29］Fujiwara D，Kato K，Nohara S，et al.The usefulness of three-dimensional cell culture in induction of cancer stem cells from esophageal squamous cell carcinoma cell lines［J］.Biochemical & Biophysical Research Communications，2013，434(4)：773-778.
［30］Zhong B，Wang T，Lun X，et al.Contribution of nestin positive esophageal squamous cancer cells on malignant proliferation，apoptosis，and poor prognosis［J］.Cancer Cell International，2014，14(1)：57.
［31］Chen Y，Jiang T，Mao A，et al.Esophageal cancer stem cells express PLGF to increase cancer invasion through MMP9 activation［J］.Tumour Biology，2014，35(12)：12749-12755.
［32］Zhang X，Komaki R，Wang L，et al.Treatment of radioresistant stem-like esophageal cancer cells by an apoptotic gene-armed，telomerase-specific oncolytic adenovirus［J］.Clinical Cancer Research，2008，14(9)：2813-2823.
［33］Wang JL，Yu JP，Sun ZQ，et al.Radiobiological characteristics of cancer stem cells from esophageal cancer cell lines［J］.World Journal of Gastroenterology，2014，36(48)：575.
［34］Chen X，Ying Z，Lin X，et al.Acylglycerol kinase augments JAK2/STAT3 signaling in esophageal squamous cells［J］.Journal of Clinical Investigation，2013，123(6)：2576-2589.
［35］Sato F，Kubota Y，Natsuizaka M，et al.EGFR inhibitors prevent induction of cancer stem-like cells in esophageal squamous cell carcinoma by suppressing epithelial-mesenchymal transition［J］.Cancer Biology & Therapy，2015，16(6)：933-940.
［36］Long A，Giroux V，Whelan KA，et al.WNT10A promotes an invasive and self-renewing phenotype in esophageal squamous cell carcinoma［J］.Carcinogenesis，2015，36(5)：598-606.