|Table of Contents|

Logistic regression analysis of benign and malignant thyroid nodules by ultrasound features

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2019 01
Page:
149-153
Research Field:
Publishing date:

Info

Title:
Logistic regression analysis of benign and malignant thyroid nodules by ultrasound features
Author(s):
Liu ChenMu QierZhang YuanxiGu JiaojiaoShi Tiemei
Department of Ultrasound,Shengjing Hospital of China Medial University,Liaoning Shenyang 110004,China.
Keywords:
three-dimensional color Doppler ultrasoundthyroid nodulesbenign and malignantLogistic regression
PACS:
R736.1
DOI:
10.3969/j.issn.1672-4992.2019.01.038
Abstract:
Objective:To evaluate the clinical significance of three-dimensional color Doppler ultrasound quantitative analysis combined with two-dimensional ultrasound in the identification of benign and malignant thyroid nodules by Logistic regression model.Methods:In 123 thyroid nodules,to compare the differences between benign and malignant in vascular index using(VI),flow index(FI),vascularization flow index(VFI) and the value of the volume by three-dimensional color Doppler ultrasound,and to observe the differences in echo,boundary,shape,aspect ratio and micro-calcification by two-dimensional ultrasound.All the statistical differences above were included in the Logistic regression model.Results:VI,FI,VFI,echo,boundary,shape,aspect ratio and micro-calcification of thyroid nodules in benign and malignant had significant difference(P<0.05),but volume not(P>0.05).Boundary,shape,aspect ratio,micro-calcification and VFI of thyroid nodules were included in Logistic regression model,and the accuracy of diagnosis of benign and malignant thyroid nodules was 91.1%.Conclusion:The three-dimensional color Doppler ultrasound quantity parameters included VI,FI and VFI which are significant in the differentiation of benign and malignant thyroid nodules.The establishment of multi-factor Logistic regression model can improve the accuracy of clinical diagnosis of benign and malignant thyroid nodules.

References:

[1]Haugen BR,Alexander EK,Bible KC,et al.American Thyroid Association(ATA) management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer[J].Thyroid,2016,26(1):1-133.
[2]Nam SJ,Yoo J,Lee HS,et al.Quantitative evaluation for differentiating malignant and benign thyroid nodules using histogram analysis of grayscale sonograms[J].Journal of Ultrasound in Medicine,2016,35:775-782.
[3]Xu YF.Capability calcification thyroid ultrasound classification in the diagnosis of benign and malignant thyroid nodules[J].China Continuing Medical Education,2016,8(17):48-50.[许亚飞.甲状腺钙化超声分型对甲状腺结节良恶性病变鉴别诊断能力的分析[J].中国继续医学教育,2016,8(17):48-50.]
[4]Remonti LR,Kramer CK,Leito CB,et al.Thyroid ultrasound features and risk of carcinoma:A systematic review and Meta-analysis of observational studies[J].Thyroid Official Journal of the American Thyroid Association,2015,25(5):538-550.
[5]Han L,Zhao H,Gong SJ.Application of two-dimensional ultrasound and three-dimensional ultrasound in diagnosis of thyroid nodules[J].Heilongjiang Medical Journal,2015,39(10):1149-1150.[韩露,赵海,宫术娟.二维超声与三维超声在甲状腺结节诊断中的应用[J].黑龙江医学,2015,39(10):1149-1150.]
[6]Palaniappan MK,Aiyappan SK,Ranga U.Role of gray scale,color Doppler and spectral Doppler in differentiation between malignant and benign thyroid nodules[J].Journal of Clinical & Diagnostic Research Jcdr,2016,10(8):TC01-TC06.
[7]Zhang B,Jiang YX,Dai Q,et al.Solid thyroid nodule:Contrast-enhanced ultrasound and immunohistochemistry[J].Chinese Journal of Medical Imaging Technology,2011,27(9):1783-1787.[张波,姜玉新,戴晴,等.甲状腺实性结节超声造影与免疫组织化学分析[J].中国医学影像技术,2011,27(9):1783-1787.]
[8]Lee JH,Shin HJ,Yoon JH,et al.Predicting lymph node metastasis in patients with papillary thyroid carcinoma by vascular index on power Doppler ultrasound[J].Head & Neck,2017,39(2):334-340.
[9]Liao B,Zeng F,Li L,et al.The correlation of vascularization index and flow index of thyroid cancer ultrasound with tumor malignancy[J].Journal of Hainan Medical University,2017,23(6):813-815.[廖冰,曾凡,黎玲,等.甲状腺癌超声血管化指数、血流指数与肿瘤恶性程度的相关关系[J].海南医学院学报,2017,23(6):813-815.]
[10]Ma Z,Liu XL,Lei P,et al.Diagnosis of three-dimensional power Doppler ultrasonography in the differential diagnosis of benign and malignant thyroid tumor[J].Med J West China,2015,27(4):574-576.[马振,刘雪玲,雷蓓,等.三维能量多普勒超声对良恶性甲状腺肿瘤的鉴别诊断[J].西部医学,2015,27(4):574-576.]
[11]Shi C,Peng GH,Cao YZ.The value of multi-mode ultrasonic technology in the diagnosis of thyroid small nodules[J].Chinese J Ultrasound Med,2015,31(11):961-963.[史策,彭格红,曹永政.多模式超声技术在甲状腺微小结节诊断中的价值[J].中国超声医学杂志,2015,31(11):961-963.]
[12]Li WB,Zhang B,Jiang YX,et al.Value of quantitative three-dimensional Doppler ultrasound in the differentiation of benign and malignant thyroid nodules[J].Acta Academiae Medicinae Sinicae,2015,37(3):300-304.[李文波,张波,姜玉新,等.三维能量多普勒超声定量分析在甲状腺良恶性结节鉴别中的应用价值[J].中国医学科学院学报,2015,37(3):300-304.]
[13]Ouyang JB,Chu YZ,Qiu QY,et al.Study on the value of superb micro-vascular imaging and ceus in differentiating benign and malignant thyroid nodules[J].Chinese J Ultrasound Med,2017,33(4):293-296.[欧阳伽保,初银珠,邱前义,等.微血管成像与超声造影在鉴别甲状腺结节良恶性的价值研究[J].中国超声医学杂志,2017,33(4):293-296.]
[14]Kamran SC,Marqusee E,Kim MI.Thyroid nodule size and prediction of cancer[J].Journal of Clinical Endocrinology & Metabolism,2013,98(2):564-570.
[15]Cavallo A,Johnson DN,White MG.Thyroid nodule size at ultrasound as a predictor of malignancy and final pathologic size[J].Thyroid,2017,27(5):641-650.
[16]Li T,Sheng JG,Li WQ,et al.The derivation and validation of a prediction rule for differential diagnosis of thyroid nodules[J].Chin J Intern Med,2013,52(11):945-950.[李拓,盛建国,李维卿,等.术前良恶性甲状腺结节鉴别诊断评分系统的建立及验证[J].中华内科杂志,2013,52(11):945-950.]

Memo

Memo:
-
Last Update: 2018-11-30