|Table of Contents|

The relationship between deep vein thrombosis and tissue factor or tissue factor pathway inhibitor in gynecologic cancer patients

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2019 01
Page:
134-137
Research Field:
Publishing date:

Info

Title:
The relationship between deep vein thrombosis and tissue factor or tissue factor pathway inhibitor in gynecologic cancer patients
Author(s):
Wang Xianghong
Department of Gynaecology and Obstetrics,General Hospital of Pingdingshan Shenma Medical Group,Henan Pingdingshan 467000,China.
Keywords:
tissue factortissue factor pathway inhibitiongynecologic tumordeep vein thrombosis
PACS:
R737.3
DOI:
10.3969/j.issn.1672-4992.2019.01.034
Abstract:
Objective:To measure the levels of tissue factor(TF),tissue factor pathway inhibitor(TFPI) of gynecologic tumor patients and to explore its relationship with gynecological malignant tumor postoperative deep venous thrombosis.Methods:From January 2013 to January 2015 in our hospital from 73 cases of gynecological malignant tumor patients as the research object,select the same period in our hospital in our hospital underwent a medical examination of 50 cases of healthy women as the control group.Of all the subjects of the study of TF,TFPI levels were detected by enzyme-linked immunosorbent assay(ELISA),and to analyze the relationship of the two and deep vein thrombosis.Results:In 9 cases of patients with postoperative deep venous thrombosis,there were 4 cases of patients with cervical cancer,3 cases of endometrial carcinoma,2 cases of ovarian cancer patients.All types of gynecological malignant tumor patients with plasma levels of TF and plasma TFPI-1 levels and TFPI activity were significantly higher than those in the control group(P<0.05).Control group of TFPI-1 levels were significantly lower than deep or no deep venous thrombosis group,and TF levels was significantly lower than that of deep vein thrombosis group(P<0.05). No deep venous thrombosis group of TF,TFPI-1 levels were significantly lower than deep venous thrombosis group(P<0.05).Conclusion:The plasma TF and TFPI-1 levels were significantly increased in patients with deep venous thrombosis after gynecological tumor surgery.TFPI-1 and TF could be used as the important indicators to predict the formation of deep venous students.

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Last Update: 2018-11-30