|Table of Contents|

Research progress on genetic diversity of COPD-related adenocarcinoma and COPD-related squamous cell carcinoma

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2018 06
Page:
975-979
Research Field:
Publishing date:

Info

Title:
Research progress on genetic diversity of COPD-related adenocarcinoma and COPD-related squamous cell carcinoma
Author(s):
Fang QiyuDeng QinfangMeng ShuyanZhou Songwen
Department of Medical Oncology,Shanghai Pulmonary Hospital,Tongji University School of Medicine,Shanghai 200433,China.
Keywords:
chronic obstructive pulmonary disease(COPD)adenocarcinomasquamous cell carcinomagenetics
PACS:
R734.2
DOI:
10.3969/j.issn.1672-4992.2018.06.041
Abstract:
Lung cancer is the leading cause of death from cancer worldwide,where non-small-cell lung cancers(NSCLCs) represent 85% of all lung cancers.Independent of smoking,chronic obstructive pulmonary disease(COPD) patients have an increased risk of NSCLCs which consist of adenocarcinoma and squamous cell carcinoma primarily.According to the distinction between COPD-related adenocarcinoma and COPD-related squamous cell carcinoma,genetic mechanism plays an important role in the development besides common causes as chronic inflammation,oxidative stress,immune response mechanism in the same causative agent.This review describes the current understanding of the difference between COPD-related adenocarcinoma and COPD-related squamous cell carcinoma from a genetical perspective.

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Last Update: 2018-01-29