|Table of Contents|

Research and progress of ITIH5 in tumor

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2018 06
Page:
950-954
Research Field:
Publishing date:

Info

Title:
Research and progress of ITIH5 in tumor
Author(s):
Yang Hua; Wang Xinlu; Shi Tiemei
Department of Ultrasound,Shengjing Hospital of China Medical University,Liaoning Shenyang 110004,China.
Keywords:
ITIH5; tumor; research progress
PACS:
R730
DOI:
10.3969/j.issn.1672-4992.2018.06.034
Abstract:
Inter-α-trypsin inhibitor H5(ITIH5),a novel member of inter-α-trypsin inhibitor(ITI) family，is a potential tumor suppressor gene，which is thought to contribute to the stability of the extracellular matrix due to the covalent linkage to hyaluronic acid(HA),participating in a variety of physiological and pathological process.Currently,many experimental studies have shown that it was involved in the process of inflammation,occurrence and metastasis of tumor.Therefore,this article reviewed the latest researches on the role of ITIH5 gene in the occurrence and development of tumor.

References:

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Memo

Memo:
National Natural Science Foundation of China（No.81501496）；国家自然科学基金资助项目（编号：81501496）
Last Update: 2018-01-29