|Table of Contents|

Adenoid cystic carcinoma of breast:A clinicopathological analysis

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2018 06
Page:
876-878
Research Field:
Publishing date:

Info

Title:
Adenoid cystic carcinoma of breast:A clinicopathological analysis
Author(s):
Wang ZhengLiu ShuangJiang Shuwan
Department of Pathology,The Affiliated Hospital of Yangzhou University,Jiangsu Yangzhou 225001,China.
Keywords:
breast neoplasmadenoid cystic carcinomahistopathologyimmunohistochemistry
PACS:
R737.9
DOI:
10.3969/j.issn.1672-4992.2018.06.015
Abstract:
Objective:To study the clinicopathological and immunohistochemical features,differential diagnosis of adenoid cystic carcinoma of breast.Methods:3 cases of breast adenoid cystic carcinoma were studied by clinical data,histopathological and immunohistochemical features.Related literatures were reviewed.Results:All 3 cases of adenoid cystic carcinoma of breast were females,age from 58 to 80 years old.All cases were grossly circumscribed and formed tubular-trabecular,cribriform,and solid-basaloid structures microscopy.The tumor typically consisted of a glandular epithelium and myoepithelial-basal cells.All glandular epithelium expressed CK7,CK5/6,CD117,myoepithelium expressed SMA,p63,basal-like cell expressed p63,CK5/6,CD117,all of which were negative for ER,PR,Her-2.3 cases of breast adenoid cystic carcinoma underwent modified radical mastectomy,there were no recurrence after surgery by follow-up.Conclusion:Adenoid cystic carcinoma of the breast is a rare subtype of breast invasive carcinoma,with a unique histopathological characteristics and favorable prognosis.

References:

[1] Canyilmaz E,Uslu GH,Memis Y,et al.Adenoid cystic carcinoma of the breast:A case report and literature review[J].Oncol Lett,2014,7(5):1600.
[2] Tang P,Yang S,Zhong X,et al.Breast adenoid cystic carcinoma in a 19-year-old man:A case report and review of the literature[J].World J Surg Oncol,2015,6:13-19.
[3] Yoo SJ,Lee DS,Oh HS,et al.Male breast adenoid cystic carcinoma[J].Case Rep Oncol,2013,6(3):514-519.
[4] Alis H,Yigitbas H,Kapan S,et al.Multifocal adenoid cystic carcinoma of the breast:An unusual presentation[J].Can J Surg,2008,51:E36-E37.
[5] Arpino G,Clark GM,Mohsin S,et al.Adenoid cystic carcinoma of the breast:Molecular markers,treatment,and clinical outcome[J].Cancer,2002,94:2119-2127.
[6] Blanco M,Egozi L,Lubin D,et al.Adenoid cystic carcinoma arising in a fibroadenoma[J].Ann Diagn Pathol,2005,9:157-159.
[7] Acs G,Simpson JF,Bleiweiss IJ,et al.Microglandular adenosis with transition into adenoid cystic carcinoma of the breast[J].Am J Surg Pathol,2003,27:1052-1060.
[8] Da Silva L,Buck L,Simpson PT,et al.Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosis[J].Virchows Arch,2009,454:107-114.
[9] Kontos M,Karles D,Petrou A,et al.Adenoid cystic carcinoma intermingled with ductal carcinoma of the breast:A case report and review of the literature[J].J Med Case Rep,2011,5:437.
[10] Brill LB,Kanner WA,Fehr A,et al.Analysis of MYB expression and MYB-NFIB gene fusions in adenoid cystic carcinoma and other salivary neoplasms[J].Mod Pathol,2011,24:1169-1176.
[11] Kosuke Miyai,Mary R Schwartz,Mukul K Divatia,et al.Adenoid cystic carcinoma of breast:Recent advances[J].World J Clin Cases,2014,2(12):732-741.
[12] Ghabach B,Anderson WF,Curtis RE,et al.Adenoid cystic carcinoma of the breast in the United States(1977 to 2006):A population-based cohort study[J].Breast Cancer Res,2010,12:R54.
[13] Khanfir K,Kallel A,Villette S,et al.Management of adenoid cystic carcinoma of the breast:A rare cancer network study[J].Int J Radiat Oncol Biol Phys,2012,82:2118-2124.
[14] Coates JM,Martinez SR,Bold RJ,et al.Adjuvant radiationtherapy is associated with improved survival for adenoid cystic carcinoma of the breast[J].J Surg Oncol,2010,102:342-347.
[15] Sun JY,Wu SG,Chen SY,et al.Adjuvant radiation therapy and survival for adenoid cystic carcinoma of the breast[J].Breast,2017,31:214-218.
[16] Kim M,Lee DW,Im J,et al.Adenoid cystic carcinoma of the breast:A case series of six patients and literature review[J].Cancer Res Treat,2014,46(1):93-97.
[17] Guo SP,Li QL,Wang YM,et al.Clinicopathologic features of adenoid cystic carcinoma of breast[J].Chin J Pathol,2017,46(1):25-28.[郭双平,李擒龙,王映梅,等.乳腺腺样囊性癌的临床病理学特点分析[J].中华病理学杂志,2017,46(1):25-28.]

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Last Update: 2018-01-29