|Table of Contents|

Analysis of clinical characteristics and prognosis for patients with hemophagocytic syndrome

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2018 04
Page:
597-599
Research Field:
Publishing date:

Info

Title:
Analysis of clinical characteristics and prognosis for patients with hemophagocytic syndrome
Author(s):
Li PeizhangWang YingPang NaiqiZhang YunLiu MiaofengZhu Chunyan
Department of Laboratory,The Affiliated Tumor Hospital of Guangxi Medical University,Guangxi Nanning 530021,China.
Keywords:
hemophagocytic syndromeclinical characteristicstreatmentprognosis
PACS:
R737.73
DOI:
10.3969/j.issn.1672-4992.2018.04.029
Abstract:
Objective:To investigate the clinical characteristics and prognosis for patients with hemophagocytic syndrome(HPS) and to improve recognition of HPS.Methods:46 patients of HPS were continuously collected at our hospital.Their laboratory data,clinical features,therapy and prognosis were analyzed.Results:Of the 46 patients,21 survived and 25 died.Compared with survival group,the size of liver and spleen were significantly enlarged in death group(P<0.05),the platelet(PLT) and fibrinogen(FIB) levels were significantly decreased in death group(P<0.05),while the lactate dehydrogenase(LDH) ,alanine aminotransferase(ALT)and serum ferritin(SF) levels were significantly increased (P<0.05).The other indicators(age,fever,WBC,Hb,AST)exhibited no statistically significance(P>0.05).Conclusion:The clinical manifestations of HPS were complex.Patients with enlargement liver or spleen,with declined FIB or PLT levels,with elevated LDH or SF levels have poor prognosis.Diagnose and treat HPS as early as possible are the key to improve prognosis.

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广西壮族自治区卫计委科研课题(编号:Z2013421)
Last Update: 2017-12-29