|Table of Contents|

Advances of lenalidomide therapy for diffuse large B cell lymphoma

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2018 01
Page:
120-123
Research Field:
Publishing date:

Info

Title:
Advances of lenalidomide therapy for diffuse large B cell lymphoma
Author(s):
Yang RonghuiLi ShiwenShen JingLiao Aijun
Department of Hematology,Shengjing Hospital of China Medical University,Liaoning Shenyang 110000,China.
Keywords:
lenalidomidediffuse large B cell lymphomarelapsed/refractoryimmune regulationchemotherapy
PACS:
R733.4
DOI:
10.3969/j.issn.1672-4992.2018.01.032
Abstract:
Lenalidomide as an immunomodulator has been widely used in multiple myeloma.It not only can directly induce the apoptosis of tumor cells,but also plays an important role in immune regulation via inflammatory cytokines,NK cells and regulatory cells.In addition,a number of basic and clinical researches confirmed that lenalidomide can also play a very important role in diffuse large B cell lymphoma (DLBCL) therapy,no matter for the newly diagnosed or relapsed/refractory DLBCL patients.Lenalidomide monotherapy or combination of R-CHOP or other regimens have achieved good results.This article is to review the advances of lenalidomide in the treatment of DLBCL.

References:

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Memo

Memo:
National Natural Science Foundation of China(No.81272629);国家自然科学基金(编号:81272629)
Last Update: 2017-11-30