|Table of Contents|

Research progress of tumor immune checkpoint therapy

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2017 06
Page:
990-993
Research Field:
Publishing date:

Info

Title:
Research progress of tumor immune checkpoint therapy
Author(s):
Jiang Huiyuan1Jiang Bin2Liu Feng2Zhang Wenying2Wang Meiling2
1.Bengbu Medical College,Anhui Bengbu 233000,China;2.Department of Oncology,Ninth People's Hospital Affiliated to Shanghai Jiaotong University,Shanghai 200000,China.
Keywords:
tumorimmune checkpointCTLA-4PD1immune checkpoint blockade
PACS:
R730.5
DOI:
10.3969/j.issn.1672-4992.2017.06.044
Abstract:
After many years of researches,the immune checkpoint treatment has finally become a clinical validated treatment of many cancer treatment methods.Immune checkpoint molecules mainly include two types:Cytotoxic T lymphocyte associated protein 4 (CTLA-4) and programmed cell death protein 1 (PD1).Antibodies to these two types of molecules have been published,and in clinical good curative effect.In this review,we mainly introduce the immune checkpoint therapy,and discuss the progress in the synergistic design of immune-targeting combination therapies.

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Last Update: 2017-01-26