|Table of Contents|

The diagnosis value of human epididymis protein 4 (HE4) level in serum and ascites of ovarian cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2017 06
Page:
937-939
Research Field:
Publishing date:

Info

Title:
The diagnosis value of human epididymis protein 4 (HE4) level in serum and ascites of ovarian cancer
Author(s):
Wei NaZhu ZhenningXue Jing
The Second Affiliated Hospital Shaanxi University of Chinese Medicine,Shaanxi Xianyang 712000,China.
Keywords:
ascitesserumHE4ovarian cancerdiagnosis
PACS:
R737.31
DOI:
10.3969/j.issn.1672-4992.2017.06.027
Abstract:
Objective:To study the diagnosis value of human epididymis protein 4 (HE4) level in serum and ascites of ovarian cancer patients.Methods:HE4 in serum and ascites of 38 ovarian cancer patients and 30 ascites benign patients were measured by euzymelinked immunosorbent assay(ELISA) and the significance of the HE4 levels were analyzed.Results:HE4 levels of cases of ovarian cancer in ascites were significantly higher than HE4 levels of ovarian cancer in serum(P<0.05).HE4 levels of ovarian cancer in serum were significantly higher than HE4 levels of benign ascites in serum(P<0.05).HE4 levels of ovarian cancer in ascites were significantly higher than HE4 levels of benign ascites in ascites(P<0.05).HE4 levels of benign ascites in ascites were not significantly higher than HE4 levels of benign ascites in serum(P>0.05).The sensitivity of HE4 ascites of ovarian cancer patients was significantly higher HE4 in serumof ovarian cancer patients.Conclusion:HE4 levels is one of important index of the diagnosis of ovarian cancer.If the level of HE4 in ascites was higher than that of serum,it was highly suspected of ovarian cancer.The HE4 level of ascites combined with serum HE4 routinely detection in patients can improve the diagnosis of ovarian cancer.

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Last Update: 2017-01-26