|Table of Contents|

The comparative research of clinicopathological features about primary liver cancer with type 2 diabetes mellitus

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2017 05
Page:
756-759
Research Field:
Publishing date:

Info

Title:
The comparative research of clinicopathological features about primary liver cancer with type 2 diabetes mellitus
Author(s):
Liu Haiting1; Wu Liping1; Liu Yanfang2; Zhang Hua1
1.Department of Geriatrics，Xijing Hospital，Fourth Military Medical University，Shaanxi Xi'an 710032，China；2.School of Public Health，Fujian Medical University，Fujian Fuzhou 350000，China.
Keywords:
primary liver cancer; type 2 diabetes mellitus; TNM staging; comparative analysis
PACS:
R735.7
DOI:
10.3969/j.issn.1672-4992.2017.05.022
Abstract:
Objective：To analye the clinicopathological features of primary liver cancer with type 2 diabetes mellitus，to provide evidence for clinical treatment.Methods：Primary data about liver cancer patients which had surgical resection and pathological diagnosis were retrospectiely analysed，compared with type 2 diabetes mellitus group (T2DM group) and without type 2 diabetes mellitus group (without T2DM group) in patients with clinically pathological features.Extract the patient's information，such as gender，age，education level，systolic blood pressure，diastolic blood pressure，smoking，drinking，BMI，Child-Pugh classification，liver laboratory tests，pathological TNM staging and so on.Results：The age in T2DM group［(58.07±9.77) years］was significant different with without T2DM group［(51.76±11.22) years，P<0.001］.There was also significant difference between the patients with T2DM group and without T2DM group in gender (P=0.003)，BMI (P<0.001)，hypertension (P<0.001)，liver cirrhosis (P<0.001)，hepatitis B (P<0.001) and AFP (P=0.003).Hepatocellular carcinoma accounted for the majority in the two groups，but there were significant differences in the proportion.The high differentiated proportion in T2DM group was higher than those without T2DM group.There was no significant difference between the two groups in smoking，drinking，education level，liver laboratory tests，Child-Pugh and TNM staging.Conclusion：Diabetes has a high incidence in liver cancer patients and is more common with elder male patients.Patients with liver cancer should pay attention to screening for type 2 diabetes or prediabetes and more concerns should be put onto type 2 diabetic mellitus patients with liver cancer.

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Memo

Memo:
国家自然科学基金（编号：81370928）
Last Update: 2017-01-26