|Table of Contents|

Comparison of clinical data of renal cell carcinoma between elderly and middle-aged and young patients

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2017 05
Page:
740-743
Research Field:
Publishing date:

Info

Title:
Comparison of clinical data of renal cell carcinoma between elderly and middle-aged and young patients
Author(s):
Li DongyangSong Yongsheng
The Second Department of Urology,Shengjing Hospital of China Medical University,Liaoning Shenyang 110004,China.
Keywords:
renal cell carcinoma (RCC)elderly patientsclinical characteristics
PACS:
R737.11
DOI:
10.3969/j.issn.1672-4992.2017.05.018
Abstract:
Objective:To investigate the clinical characteristics of elderly patients with renal cell carcinoma(RCC),and to elevate the level of diagnosis and treatment of RCC in elderly patients.Methods:A retrospective analysis was performed in our hospital from June 2011 to May 2016,which contained 113 cases of elderly (≥60 years old) and 107 cases of middle-aged and youth (<60 years old).Compared and analyzed the clinical and pathological data of these patients with RCC.Results:The proportion of asymptomatic RCC elderly patients was significantly lower than that in the middle and young age (P<0.01).Elderly patients' clear cell carcinoma grade 3-4 ratio was significantly higher than that in middle-aged and youth (P<0.01). The intraoperative blood loss and postoperative hospitalization time of elderly patients with RCC was significantly different between that in middle-aged and young patients with RCC (P<0.01).Conclusion:More elderly patients with RCC had first symptoms,higher progressive histopathological grading,intraoperative blood loss and postoperative hospitalization time than middle-aged and young patients.Physical examination and early diagnosis and treatment can improve the quality of life of elderly patients with RCC.

References:

[1]Na YQ,Ye ZQ.The 2014 edition of the Chinese department of urology disease diagnosis and treatment guide manual[M].Beijing:People's Health Publishing House,2013:3-5.[那彦群,叶章群.2014版中国泌尿外科疾病诊断治疗指南手册[M].北京:人民卫生出版社,2013:3-5.]
[2]Kotb AF,Attia D,Hashad MM,et al.Renal cell carcinoma:Are we attacking a different tumor over the past 10 years[J]?Int J Health Sci,2016,10(2):191-195.
[3]Lan XP,Jiang W,Sun Z,et al.Clinical features and diagnosis and teatment of renal cancer patients in different age groups (young,middle-aged and elderly)[J].Urol J (Electronic Edition),2013,5(04):4-8.[兰晓鹏,蒋伟,孙桢,等.各年龄段(青年、中年、老年)肾癌患者临床特征及诊治分析[J].泌尿外科杂志(电子版),2013,5(04):4-8.]
[4]Donin NM,Suh LK,Barlow L,et al.Tumour diameter and decreased preoperative estimated glomerular filtration rate are independently correlated in patients with renal cell carcinoma[J].BJU Int,2012,109(3):379-383.
[5]Liang K,Wang F,Xu H,et al.Study on the application value of 99Tcm-DTPA renal dynamic imaging and renal tumor grading system in the operation of kidney preserving units[J].Med Equipment in Chin,2015,30(12):38-40.[梁凯,王峰,徐辉,等.99Tcm-DTPA肾动态显像和肾脏肿瘤评分系统在保留肾单位手术中的应用价值研究[J].中国医疗设备,2015,30(12):38-40.]
[6]Gao XY.Preoperative evaluation of renal function in patients with renal dynamic imaging[J].Med Informat,2015,15(20):212.[高小勇.术前肾动态显像评价肾功能对肾脏手术方案指导价值[J].医学信息,2015,15(20):212.]
[7]Low G,Huang G,Fu W,et al.Review of renal cell carcinoma and its common subtypes in radiology[J].World J Radiol,2016,8(5):484-500.
[8]Rodriguez A,Tazi H,Patard JJ,et al.Renal cell carcinoma in adults less than 40 years of age:a particular cancer? Incidence,outcome and review of the literature[J].Ann Uro,2003,37(4):155-159.
[9]Wei BL,Guan ZC.Analysis and comparison of pathological characteristics of renal cell carcinoma in young and old patients[J].Medical Information (Middle Monthly J),2010,5(05):1051-1053.[魏本林,关志忱.青年与老年肾癌的病理特点分析比较[J].医学信息(中旬刊),2010,5(05):1051-1053.]
[10]Gillett MD,Cheville JC,Karnes RJ,et al.Comparison of presentation and outcome for patients 18 to 40 and 60 to 70 years old with solid renal masses[J].Urol,2005,173:1893-1896.
[11]Jae Hee Suh,Tina OAk,Jae Y,et al.Clinicopathologic features of renal cellcarcinoma in young adults:a comparison study with renal cell carcinoma in older patients[J].Int J Clin Exp Pathol,2009,2:489-493.
[12]Sutherland SE,Resnick MI,Maclennan GT.Dose the size of the surgical margin in partial nephrectomy for renal cell cancer really matter[J]?Urology,2002,167(1):61-64.
[13]Rodríguez-Covarrubias F,Rivera-Ramirez JA,Gabilondo-Pliego B,et al.Surgical treatment of renal-cell carcinoma in elderly people[J].Actas Urol Esp,2016,40(6):395-399.
[14]Xie WF,Liu ZW,Pan J,et al.Safety and short term efficacy of laparoscopic versus open partial nephrectomy in the treatment of small renal cell carcinoma[J].J Minimally Invasive Medicine,2015,10(04):507-508.[谢文锋,刘卓炜,潘杰,等.腹腔镜与开放性肾部分切除术治疗小肾癌的安全性与近期疗效比较[J].微创医学,2015,10(04):507-508.]

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Last Update: 2017-01-26