|Table of Contents|

An analysis of features and risk factors for neck lymph node metastasis in papillary thyroid carcinoma

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2017 05
Page:
709-712
Research Field:
Publishing date:

Info

Title:
An analysis of features and risk factors for neck lymph node metastasis in papillary thyroid carcinoma
Author(s):
Yan WeiJiang TaoZheng Xiao
Department of Endocrinology,Beijing Shijitan Hospital of Capital Medical University,Beijing 100038,China.
Keywords:
papillary thyroid carcinomalymphatic metastasisrisk factorscentral lymph node metastasislateral lymph node metastasis
PACS:
R736.1
DOI:
10.3969/j.issn.1672-4992.2017.05.009
Abstract:
Objective:To investigate features and risk factors for regional neck lymph node metastasis in papillary thyroid carcinoma.Methods:The data of 404 patients with PTC who were treated in Beijing Shijitan Hospital from January 2010 to December 2014 were retrospectively analyzed.The relationship among the neck lymph node metastasis of different area and patient's gender,age,preoperative TSH level,tumor max diameter,multifocality,capsular invasion,PTC with Hashimotos Thyroiditis,PTC with nodular goiter were analyzed.Results:When PTC associated with neck lymph node metastasis,most of them metastasis to central lymph node metastasis,followed by lateral lymph node metastasis.The transfer rate of region Ⅲ and Ⅳ was equivalent and higher than region Ⅱ.The univariate analyses of neck lymph node metastasis results showed that gender,tumor max diameter,multifocality,capsular invasion,PTC with nodular goiter were statistically significantly related to both central lymph node metastasis and lateral lymph node metastasis(P<0.05).While age was statistically significantly related to central lymph node metastasis(P<0.05).For lateral lymph node metastases,the PTC with hashimotos thyroiditis were statistically significant(P<0.05).The multivariate Logistic regression analysis showed that male patient's age<45 years old,tumor max diameter>1cm and multifocality were risk factors for central lymph node metastasis(P<0.05).For lateral lymph node metastasis,the multifocality,capsular invasion and associated with Hashimotos Thyroiditis were risk factors(P<0.05).Conclusion:The male patient's age<45 years old,tumor max diameter>1cm and multifocality might increase the risk of central lymph node metastasis.When patients with multifocality,capsular invasion,associated with Hashimotos Thyroiditis,suspicious skip metastasis or with central lymph node metastasis,we should pay attention to the risk of lateral lymph node metastases.

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Last Update: 2017-01-26