|Table of Contents|

The value of SWI,3D-ASL and IVIM in the classification of glioma

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 04
Page:
741-747
Research Field:
Publishing date:

Info

Title:
The value of SWI,3D-ASL and IVIM in the classification of glioma
Author(s):
DU Changyue1; QI Xuhong2; WEN Zhiyong2; WANG Rengui1
1.Department of Radiology,Beijing Shijitan Hospital,Capital Medical University,Beijing 100038,China;2.Department of Radiology,Electric Power Teaching Hospital,Capital Medical University，Beijing 100073,China.
Keywords:
glioma grading; three-dimensional arterial spin labeling imaging; susceptibility weighted imaging; intravoxel incoherent motion
PACS:
R739.4
DOI:
10.3969/j.issn.1672-4992.2023.04.028
Abstract:
Objective:To evaluate the value of susceptibility weighted imaging(SWI),three-dimensional arterial spin labeling(3D-ASL)and intravoxel incoherent motion(IVIM)in identification of gliomas.Methods:92 patients with glioma(35 grade II,13 grade III and 44 grade IV)were enrolled in this study.All patients underwent SWI,3D-ASL and IVIM before operation,then measured intratumoral susceptibility signal intensity(ITSS)scores,the maximum tumor blood flow(TBFmax),the fast apparent diffusion coefficient(fast ADC),slow apparent diffusion coefficient(slow ADC)and perfusion fraction(f).TBFmax was also normalized to the corresponding values in contralateral normal white matter(r1),grey matter(r2),and mirror regions(r3).These parameters were compared to seek differences between grade II vs grade III,grade III vs grade IV,and grade II vs grade IV tumors.Receiver operating characteristic(ROC)curve analysis was used to evaluate the performance of these parameters.Results:ITSS scores were statistically different between grade II vs grade III,grade III vs grade IV,and grade II vs grade IV tumors,and higher grades of gliomas showed higher ITSS scores(P<0.05).Fast ADC values,slow ADC values and f values were statistically different between grade II vs grade III and grade II vs grade IV tumors(P<0.05).But TBFmax,r1,r2 and r3 were statistically significant just between grade II vs grade IV(P<0.05).Slow ADC provided the highest AUC for the discrimination of grade II vs III(0.94).ITSS scores provided the highest AUC for the discrimination of grade II vs IV(0.96).The area under AUC of the ITSS scores between grade III vs IV was 0.72.Conclusion:The parameters of SWI,3D-ASL and IVIM can be used to differentiate gliomas.By combing three models,the diagnostic efficacy of grading gliomas was greatest than that of a single technique.

References:

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