|Table of Contents|

The value of dual time point 18F-FDG PET/CT in differentiating benign and malignant gastric lesions

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 04
Page:
747-751
Research Field:
Publishing date:

Info

Title:
The value of dual time point 18F-FDG PET/CT in differentiating benign and malignant gastric lesions
Author(s):
Adila·Adili; LI Xiaohong; QIN Yongde; Nazi·Yilihamu; ZHANG Lei
Department of Nuclear Medicine,the First Affiliated Hospital of Xinjiang Medical University,Xinjiang Urumqi 830011,China.
Keywords:
18F-FDG; PET/CT; standardized uptake value; dual time point; gastric lesions
PACS:
R735.2
DOI:
10.3969/j.issn.1672-4992.2023.04.029
Abstract:
Objective:To evaluate the value of dual time point(DTP)18F-FDG PET/CT in differentiating benign and malignant gastric lesions.Methods:A total of 106 pathologically confirmed benign and malignant gastric lesions with DTP 18F-FDG PET/CT were included for retrospective analysis,81 with malignant lesions and 25 with benign lesions.Gastric adenocarcinoma cases were classified into MGC and Non-MGC according to pathological findings,and SUVearly and SUVdelayed of gastric lesions were measured,Retention Index(RI) was calculated,and ROC curves were plotted to obtain the optimal diagnostic cut-off value and diagnostic efficacy.Results:The THKmax,SUVearly,SUVdelayed and RI of benign gastric lesions were lower than those of malignant gastric lesions,and the differences were statistically significant(P<0.05).There was no significant difference in the range of lesions(P>0.05).The SUVearly,SUVdelayed and RI of MGC were lower than those of Non-MGC,and the differences were statistically significant(P<0.05)，there was no significant difference in the range of lesions and THKmax(P>0.05).The optimal cut-off value of SUVearly for differentiating benign and malignant lesions was 7.95,with a sensitivity of 61.7%,specificity of 92.0%,and accuracy of 67.9%.The optimal cut-off value of RI was 0.229,with a sensitivity of 67.9%,specificity of 88.0%,and accuracy of 71.7%.The SUVearly optimal cut-off value for identifying MGC from Non-MGC was 8.65,which had a sensitivity of 74.4%,specificity of 91.7%,and accuracy of 80.6%,and the RI was 0.228,which had a sensitivity of 88.4%,specificity of 58.3%,and accuracy of 77.6%.Conclusion:DTP 18F-FDG PET/CT has certain value in differentiating benign and malignant gastric lesions.

References:

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Memo:
新疆维吾尔自治区自然科学基金资助项目（编号：2019D01C307）
Last Update: 1900-01-01