|Table of Contents|

A review about the key factors of carcinoma of human papillomavirus

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2020 05
Page:
851-854
Research Field:
Publishing date:

Info

Title:
A review about the key factors of carcinoma of human papillomavirus
Author(s):
Yu MiaoSun Zhengrong
Biobank,Affiliated Shengjing Hospital,China Medical University,Liaoning Shenyang 110004,China.
Keywords:
human papillomaviruscervical cancergene functioncarcinogenic mechanism
PACS:
R730.2
DOI:
10.3969/j.issn.1672-4992.2020.05.038
Abstract:
Human papillomavirus (HPV) infection is associated with a variety of diseases.High-risk human papillomavirus is closely related to various cancers such as head and neck squamous cell carcinoma and anogenital carcinoma.However,the correlation with cervical cancer is particularly significant.The human papillomavirus genome is divided into an early gene coding region (E),a late gene coding region (L) and a long control region (LCR).It makes the normal cervix develop into cervical cancer eventually by the function of these genes and its interaction with the host cells.Therefore,a large amount of work is carried out.This article will review the current research results on the role of various parts of the HPV genome and those carcinogenic mechanisms.

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辽宁省高等学校基本科研项目(编号:LFWK201710);辽宁省重点研发计划指导计划项目(编号:2018225009)
Last Update: 1900-01-01