|Table of Contents|

The incidence of contrast-induced nephropathy and analysis of related risk factors in patients with cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2019 01
Page:
120-123
Research Field:
Publishing date:

Info

Title:
The incidence of contrast-induced nephropathy and analysis of related risk factors in patients with cancer
Author(s):
Dong WenxiaYu YafenPeng JunqiongQian XinfengChu LapingLi JunZhou LifangWang Ruoyu
Division of Nephrology,Affiliated Hospital of Jiangnan University,Jiangsu Wuxi 214062,China.
Keywords:
contrast mediumacute kidney injurytumor patientsprognosisrisk factoretiology
PACS:
R730.7
DOI:
10.3969/j.issn.1672-4992.2019.01.030
Abstract:
Objective:To investigate the prevelance and prognosis of patients with tumor in our hospital who were diagnosised with contrast-induced nephropathy(CIN) and to explore the related risk factors which may predict the prognosis and help to get insight of the distribution of etilogy and clinical features in CIN.Methods: The patients with tumor and full histories were enrolled in the study as study subjects by our hospital medical record information system screening from Jan to Dec 2016.We analyzed the incidence of CIN,etiology and distribution characteristics,prognosis retrospectively.The Logistic regression models were used to analyzed the risk factors which may influence the prognosis of CIN and renal function.Results: 36 patients were selected among 12 048 patients with tumor.The incidence of CIN was 0.299%.There were 9 patients gave up the treatment in the end and 7 patients died,20 patients had lived through the whole therapy.15 patients had recovered their renal function,5 patients partly recovered,16 cannot recover forever.By comparison we got to know that the stage of acute kidney injury(AKI) was associtated with the prognosis of renal outcome,the higher stage always means more mortality,especially in patients with hypotension.Age,the stage of AKI and hypotension were all statistically correlated with renal outcome by Chi-square test.But after correction of multi-factor,AKI stage was statistically associated with renal outcomes of patients of CIN,the multi-factor Logistic regression analysis also suggests the same conclusion.Conclusion: The study found that the prognosis of patients with CIN can result poor and renal damage.The AKI stage and low blood pressure are directly related to the prognosis of patients with CIN,and AKI stage is an obvious risk factor for renal outcome.

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Last Update: 2018-11-30