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Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:

2017 10

Page:

1662-1666

Research Field:

Publishing date:

Info

Title:

Progress in the identification of clonal origin and treatment of multifocal hepatocellular carcinoma

Author(s):

Fan Yongguo¹; Zhou Feng¹; Zhai Yulong¹; Shi Wencong¹; Dang Ling¹; Du Xiaohong²; He Xianli¹

1.Department of General Surgery,Tangdu Hospital,The Fourth Military Medical University,Shaanxi Xi'an 710038,China,2.Teaching and Experiment Center,The Fourth Military Medical University,Shaanxi Xi'an 710032,China.

Keywords:

hepatocellular carcinoma; multicentric origin (MO); intrahepatic metastasis (IM)

PACS:

R735.7

DOI:

10.3969/j.issn.1672-4992.2017.10.039

Abstract:

Hepatocellular carcinoma (HCC) is one of the most common malignancies in the world.It has the characteristics of occult onset and rapid development.Most of the patients have been diagnosed too late.In addition,about half of primary liver cancer patients,especially hepatocellular carcinoma,showed multiple nodular lesions.The patients could be devided into intrahepatic metastasis (IM) or multicentric origin (MO),according to different origins.The treatment and prognosis of these two groups are significantly different.Therefore,the identification of the origin of multi-nodular liver cancer play very important role in improving the quality of life of patients.This article mainly reviews the relevant papers about classification and differential diagnosis of multifocal occurrence and summarizes their potential clinical value in treatment.

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Memo

Memo:

国家自然科学基金青年项目(编号：81402328);陕西省科技统筹创新工程计划项目(编号：2016KTZDS-F01-04)

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Last Update: 2017-04-01