|Table of Contents|

Analysis of the therapeutic effect of complete laparoscopic nephroureterectomy for upper urinary tract urothelial carcinoma

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2024 24
Page:
4644-4648
Research Field:
Publishing date:

Info

Title:
Analysis of the therapeutic effect of complete laparoscopic nephroureterectomy for upper urinary tract urothelial carcinoma
Author(s):
LEI Ting1; XIE Jiaokui1; WANG Xiao1; QIU Minghao1; ZHANG Yupu1; DENG Jiuhan1; WANG Chunyang2;  FU Weijun2
1.Department of Urology,Ankang Central Hospital，Shaanxi Ankang 725000,China;2.The First Medical Center of the General Hospital of the Chinese People's Liberation Army，Beijing 100000,China.
Keywords:
upper urinary tract urothelial carcinoma; laparoscopy; total nephroureterectomy
PACS:
R737.11
DOI:
10.3969/j.issn.1672-4992.2024.24.010
Abstract:
Objective:To evaluate the clinical efficacy of complete laparoscopic nephroureterectomy for upper urinary tract urothelial carcinoma (UUT-UC).Methods:We retrospectively analysed the clinical case data of 64 patients with UUT-UC from January 2011 to October 2023 in our hospital and from August 2016 to February 2020 in the First Medical Center of the General Hospital of the Chinese People's Liberation Army,and then divided them into two groups according to the choice of different laparoscopic surgical modalities.Patients in control group (n=40) underwent transurethral electrodesiccation cystectomy with sleeve resection+posterior laparoscopic nephroureterectomy with full-length resection+transperitoneal laparoscopic nephroureterectomy.Patients in observation group (n=24) underwent complete laparoscopic nephroureterectomy with full-length resection+sleeve resection of the inner segment of the bladder wall+middle laparoscopic nephroureterectomy of the lower abdomen.The two groups of surgical time,bleeding volume,postoperative drainage volume,postoperative exhaust time,average hospital stay and recurrence rate of urinary tract urothelial carcinoma were compared.Results:The operation time of the observation group was significantly shorter than that of the control group (mean 124 min versus 166 min,P<0.05),the bleeding volume was significantly lower (mean 46 mL versus 86 mL,P<0.05),the postoperative drainage volume was less (mean 68 mL versus 142 mL,P<0.05),and the mean hospital stay was shorter (mean 5.4 d versus 6.8 d,P<0.05).The postoperative venting time and the recurrence rate of uroepithelial cancer were not statistically significant in both groups (P>0.05).Conclusion:Transabdominal complete laparoscopic nephroureterectomy for the treatment of UUT-UC has the advantages of short operation time,low bleeding and fast postoperative recovery,which is a safe and effective minimally invasive surgical treatment in clinic,and it is worth to be popularised and applied in clinic.

References:

［1］苗腾飞,王利辉,李云龙,等.经腹腔腹腔镜单一体位肾输尿管全长切除术加膀胱袖套切除术治疗上尿路尿路上皮癌临床疗效分析［J］.肿瘤基础与临床,2022,35(3):244-247. MIAO TF,WANG LH,LI YL,et al.Clinical efficacy analysis of laparoscopic single position nephroureterectomy combined with bladder sleeve resection for the treatment of upper urinary tract urothelial carcinoma ［J］.Tumor Fundamentals and Clinical Practice,2022,35(3):244-247.
［2］CLAYMAN RV,KAVOUSSI LR,FIGENSHAU RS,et al.Laparoscopic nephroureterectomy:initial clinical case report［J］.J Laparoendosc Surg,1991,1(6):343-349.
［3］姜云中,屈小微,姚紫川,等.开放手术与后腹腔镜手术治疗器官局限性上尿路上皮癌的疗效比较［J］.现代肿瘤医学,2021,29(21):3777-3781. JIANG YZ,QU XW,YAO ZC,et al.Comparison of the therapeutic effects of open surgery and retroperitoneal laparoscopic surgery for organ localized upper urinary tract epithelial cancer［J］.Modern Oncology,2021,29(21):3777-3781.
［4］尚义超,尚攀峰,郑铎,等.不同腹腔镜术式治疗上尿路尿路上皮癌的比较研究［J］.中国微创外科杂志,2021,21(4):293-297. SHANG YC,SHANG PF,ZHENG D,et al.Comparative study of different laparoscopic procedures for the treatment of upper urinary tract urothelial carcinoma［J］.Chinese Journal of Minimally Invasive Surgery,2021,21(4):293-297.
［5］ZHAO Y,DENG FM,MELAMED J,et al.Diagnostic role of urine cytology and ureteroscopic biopsies in detection of high grade upper tract urothelial carcinoma［J］.American Journal of Clinical and Experimental Urology,2021,9(3):221-228.
［6］TSUJIHATA M,NONOMURA N.Laparoscopic nephroureterectomy for upper tract transitional cell carcinoma comparison of laparoscopic and open surgery［J］.Eur Uro,2006,49:332-336.
［7］BAE H,CHUNG JH,SONG W,et al.Robotic radical nephroureterectomy with bladder cuff excision for upper tract urothelial carcinoma:A trend analysis of utilization and a comparative study［J］.Cancers,2022,14(10):2497.
［8］HATTORI R,YOSHINA Y,GOTOH M,et al.Laparoscopic nephroureterectomy for transitional cell carcinoma of pelvis and ureter:Nagoya experience［J］.Urology,2006,67(4):701-705.
［9］MCNEILL SA,CHRISOFOS M,TOLLEY DA.The long-term outcome after laparoscopic nephroureterectomy:a comparison with open nephroureterectomy ［J］.BJU Int,2000,86(6):619-623.
［10］洪宝发，王晓雄.肾输尿管全长切除术治疗肾盂输尿管癌（附39例报告）［J］.中华泌尿外科杂志，2000,21（6）：334-335. HONG BF,WANG XX.Total length nephrectomy for the treatment of renal pelvis and ureteral cancer (report of 39 cases)［J］.Chinese Journal of Urology，2000,21（6）：334-335.
［11］陈策，孙颖浩，许传亮.后腹腔镜联合膀胱电切镜治疗上尿路移行细胞癌［J］.中国内镜杂志，2005,11（5）：474-478. CHEN C,SUN YH,XU CL.Laparoscopic combined with bladder resection for the treatment of upper urinary tract transitional cell carcinoma［J］.Chinese Journal of Endoscopy，2005,11（5）：474-478.
［12］马潞林，黄毅，卢剑，等.后腹腔镜下肾输尿管全长及膀胱袖状切除术35例报告［J］.中华泌尿外科杂志，2006,27（07）:450-452. MA LL，HUANG Y,LU J,et al.Laparoscopic nephroureterectomy and bladder sleeve resection:a report of 35 cases［J］.Chinese Journal of Urology，2006,27（07）:450-452.
［13］ZHAO Y,DENG FM,MELAMED J,et al.Diagnostic role of urine cytology and ureteroscopic biopsies in detection of high grade upper tract urothelial carcinoma［J］.American Journal of Clinical and Experimental Urology,2021,9(3):221-228.
［14］刘荣耀.经腹腔完全腹腔镜肾输尿管全长切除术治疗上尿路尿路上皮癌［J］.北京大学学报（医学版）,2011,8(4):532-534. LIU RY.Laparoscopic total nephrectomy for the treatment of upper urinary tract urothelial carcinoma［J］.Journal of Peking University (Medical Edition),2011,8(4):532-534.
［15］XIAO C,WANG Y,HUA M,et al.Complete transperitoneal laparoscopic nephroureterectomy in a single position for upper urinary tract urothelial carcinoma and comparative outcomes［J］.World Journal of Surgical Oncology,2021,19(1):195.

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