［1］ MOUFARRIJ S,DANDAPANI M,ARTHOFER E,et al.Epigenetic therapy for ovarian cancer:promise and progress［J］.Clin Epigenetics,2019,11(1):7.
［2］ RAHANGDALE L,MUNGO C,O'CONNOR S,et al.Human papillomavirus vaccination and cervical cancer risk［J］.BMJ,2022,379:e070115.
［3］ MAKKER V,MACKAY H,RAY-COQUARD I,et al.Endometrial cancer［J］.Nat Rev Dis Primers,2021,7(1):88.
［4］ SAIBIL H.Chaperone machines for protein folding,unfolding and disaggregation［J］.Nat Rev Mol Cell Biol,2013,14(10):630-642.
［5］ KUBOTA H.Function and regulation of cytosolic molecular chaperone CCT［J］.Vitam Horm,2002,65:313-331.
［6］ LIU J,HUANG L,ZHU Y,et al.Exploring the expression and prognostic value of the TCP1 ring complex in hepatocellular carcinoma and overexpressing its subunit 5 promotes HCC tumorigenesis［J］.Front Oncol,2021,11:739660.
［7］ LI Y,LIU C,ZHANG X,et al.CCT5 induces epithelial-mesenchymal transition to promote gastric cancer lymph node metastasis by activating the Wnt/beta-catenin signalling pathway［J］.Br J Cancer,2022,126(12):1684-1694.
［8］ MENG Y,YANG L,WEI X,et al.CCT5 interacts with cyclin D1 promoting lung adenocarcinoma cell migration and invasion［J］.Biochem Biophys Res Commun,2021,567:222-229.
［9］ OOE A,KATO K,NOGUCHI S.Possible involvement of CCT5,RGS3,and YKT6 genes up-regulated in p53-mutated tumors in resistance to docetaxel in human breast cancers［J］.Breast Cancer Res Treat,2007,101(3):305-315.
［10］ WANG Z,YANG L,HUANG Z,et al.Identification of prognosis biomarkers for high-grade serous ovarian cancer based on stemness［J］.Front Genet,2022,13:861954.
［11］ CONG Y,BAKER ML,JAKANA J,et al.4.0-A resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement［J］.Proc Natl Acad Sci USA,2010,107(11):4967-4972.
［12］ GESTAUT D,ZHAO Y,PARK J,et al.Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT［J］.Cell,2022,185(25):4770-87 e20.
［13］ KUBOTA H,HYNES GM,KERR SM,et al.Tissue-specific subunit of the mouse cytosolic chaperonin-containing TCP-1［J］.FEBS Lett,1997,402(1):53-56.
［14］ DITZEL L,LOWE J,STOCK D,et al.Crystal structure of the thermosome,the archaeal chaperonin and homolog of CCT［J］.Cell,1998,93(1):125-138.
［15］ PARK J,KIM H,GESTAUT D,et al.A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle［J］.Nat Commun,2024,15(1):1007.
［16］ SMITH TM,WILLARDSON BM.Mechanistic insights into protein folding by the eukaryotic chaperonin complex CCT［J］.Biochem Soc Trans,2022,50(5):1403-1414.
［17］ SERGEEVA OA,CHEN B,HAASE-PETTINGELL C,et al.Human CCT4 and CCT5 chaperonin subunits expressed in Escherichia coli form biologically active homo-oligomers［J］.J Biol Chem,2013,288(24):17734-17744.
［18］ MA X,LU C,CHEN Y,et al.CCT2 is an aggrephagy receptor for clearance of solid protein aggregates［J］.Cell,2022,185(8):1325-1345 e22.
［19］ JIN M,LIU C,HAN W,et al.TRiC/CCT chaperonin:structure and function［J］.Subcell Biochem,2019,93:625-654.
［20］ LLORCA O,SMYTH MG,MARCO S,et al.ATP binding induces large conformational changes in the apical and equatorial domains of the eukaryotic chaperonin containing TCP-1 complex［J］.J Biol Chem,1998,273(17):10091-10094.
［21］ARAKI K, WATANABE-NAKAYAMA T, SASAKI D, et al. Molecular dynamics mappings of the CCT/TRiC complex-mediated protein folding cycle using diffracted X-ray tracking［J］.Int J Mol Sci,2023,24(19):14850.
［22］ JAYASINGHE M,TEWMEY C,STAN G.Versatile substrate protein recognition mechanism of the eukaryotic chaperonin CCT［J］.Proteins,2010,78(5):1254-1265.
［23］ UCHIKADO Y,INOUE H,HARAGUCHI N,et al.Gene expression profiling of lymph node metastasis by oligomicroarray analysis using laser microdissection in esophageal squamous cell carcinoma［J］.Int J Oncol,2006,29(6):1337-1347.
［24］ GUAN B, XU M, ZHENG R, et al. Novel biomarkers to predict treatment response and prognosis in locally advanced rectal cancer undergoing neoadjuvant chemoradiotherapy［J］. BMC Cancer,2023,23(1):1099.