|Table of Contents|

Correlation analysis of inflammatory indicators,gallbladder polyps and colorectal cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2024 10
Page:
1847-1854
Research Field:
Publishing date:

Info

Title:
Correlation analysis of inflammatory indicators,gallbladder polyps and colorectal cancer
Author(s):
LI Yan; NAN Qiong; CHEN Zihong; ZHANG Yahan; XIAO Lian
Department of Gastroenterology，the First Affiliated Hospital of Kunming Medical University，Yunnan Institute of Digestive Diseases，Yunnan Kunming 650032，China.
Keywords:
colorectal cancer; inflammatory indicators; neutrophil-to-lymphocyte ratio (NLR); systemic immune inflammation index (SII); gallbladder polyps
PACS:
R735.3
DOI:
10.3969/j.issn.1672-4992.2024.10.015
Abstract:
Objective：To study the changes of blood routine inflammatory indicators and the occurrence of gallbladder polyps in patients with colorectal cancer,and to explore the correlation between inflammatory indicators,gallbladder polyps and colorectal cancer.Methods:This study retrospectively analyzed 145 cases of colorectal cancer patients and 186 cases of healthy individuals with normal colonoscopy results.The general conditions,neutrophil-to-lymphocyte ratio (NLR),platelet-to-lymphocyte ratio (PLR),monocyte-to-lymphocyte ratio (MLR),systemic immune inflammation index (SII),and gallbladder diseases (post-cholecystectomy status,gallbladder polyps,gallbladder stones) were statistically compared and analyzed between the two groups of research subjects.Results:Blood routine inflammatory indicators were higher in the colorectal cancer group than in the control group.The high levels of NLR,SII and the presence of gallbladder polyps and gallbladder stones were important factors for colorectal carcinogenesis,independently of post-cholecystectomy status.The number of gallbladder polyps was relatively higher in the colorectal cancer group and their diameters were larger.The gallbladder polyps were more frequent in the colon cancer group than in the rectal cancer group.Conclusion:There is a correlation between inflammatory indicators,gallbladder polyps and colorectal cancer,and gallbladder polyps combined with SII are informative for screening people at high risk of colorectal cancer.

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