［1］ALNUAIMI AR,NAIR VA,MALHAB LJB,et al.Emerging role of caldesmon in cancer:A potential biomarker for colorectal cancer and other cancers［J］.World J Gastrointest Oncol,2022,14(9):1637-1653.
［2］LIU S,ZHONG Z,ZHANG C,et al.Targeted therapy for the treatment of gliomas with multifunctional orange emissive carbon dots［J］.Nanoscale Adv,2021,4(3):894-903.
［3］VIRTUOSO A,DE LUCA C,CIRILLO G,et al.Tumor microenvironment and immune escape in the time course of glioblastoma［J］.Mol Neurobiol,2022,59(11):6857-6873.
［4］MURK K,HULSE R.Forced but effective partners in crime:How astrocytes drive the progression of glioblastoma［J］.Brain,2022,145(9):2952-2954.
［5］WANG D,ZHAO Q,QIN J,et al.Urokinase loaded black phosphorus nanosheets for sequential thrombolysis and reactive oxygen species scavenging in ischemic stroke treatment［J］.Biomater Sci,2022,10(16):4656-4666.
［6］CHEN X,FAN X,ZHANG Y,et al.Cooperative coordination-mediated multi-component self-assembly of "all-in-one" nanospike theranostic nano-platform for MRI-guided synergistic therapy against breast cancer［J］.Acta Pharm Sin B,2022,12(9):3710-3725.
［7］ZHAO X,WU J,ZHANG K,et al.The synthesis of a nanodrug using metal-based nanozymes conjugated with ginsenoside Rg3 for pancreatic cancer therapy［J］.Nanoscale Adv,2021,4(1):190-199.
［8］ZHAO L,GU X,JIANG F,et al.Long-lasting proteinaceous nanoformulation for tumor imaging and therapy［J］.ACS Omega,2022,7(35):31299-31308.
［9］NAZEMOROAYA Z,SARAFBIDABAD M,MAHDIEH A,et al.Use of saponinosomes from ziziphus spina-christi as anticancer drug carriers［J］.ACS Omega,2022,7(32):28421-28433.
［10］YAN X,QI Y,REN L,et al.Silver nanoclusters show advantages in macrophage tracing in vivo and modulation of anti-tumor immuno-microenvironment［J］.J Control Release,2022,348:470-482.
［11］PANDA J,SATAPATHY BS,SARKAR R,et al.A zinc ferrite nanodrug carrier for delivery of docetaxel:Synthesis,characterization,and in vitro tests on C6 glioma cells［J］.J Microencapsul,2022,39(2):136-144.
［12］MATALQAH SM,AIEDEH K,MHAIDAT NM,et al.Preparation of modified chitosan-based nanoparticles for efficient delivery of doxorubicin and/or cisplatin to breast cancer cells［J］.Curr Cancer Drug Targets,2022,22(2):133-141.
［13］PANDA S,BHOL CS,BHUTIA SK,et al.DSPE-PEG-coated uniform nitrogen-doped carbon capsules for NIR-mediated synergistic chemophototherapy of skin cancer［J］.ACS Appl Bio Mater,2021,4(9):7059-7069.
［14］SZALAY AS,TAUBE JM.Data-rich spatial profiling of cancer tissue:Astronomy informs pathology［J］.Clin Cancer Res,2022,28(16):3417-3424.
［15］SANTANA-KRIMSKAYA SE,KAWAS JR,ZARATE-TRIVINO DG,et al.Orthotopic and heterotopic triple negative breast cancer preclinical murine models:A tumor microenvironment comparative［J］.Res Vet Sci,2022,152:364-371.
［16］HARRIS MA,KUANG H,SCHNEIDERMAN Z,et al.ssDNA nanotubes for selective targeting of glioblastoma and delivery of doxorubicin for enhanced survival［J］.Sci Adv,2021,7(49):eabl5872.
［17］YE Z,GAO L,CAI J,et al.Esterase-responsive and size-optimized prodrug nanoparticles for effective intracranial drug delivery and glioblastoma treatment［J］.Nanomedicine,2022,44:102581.
［18］MOJARAD-JABALI S,FARSHBAF M,HEMMATI S,et al.Comparison of three synthetic transferrin mimetic small peptides to promote the blood-brain barrier penetration of vincristine liposomes for improved glioma targeted therapy［J］.Int J Pharm,2022,613:121395.
［19］FARSHBAF M,MOJARAD-JABALI S,HEMMATI S,et al.Enhanced BBB and BBTB penetration and improved anti-glioma behavior of Bortezomib through dual-targeting nanostructured lipid carriers［J］.J Control Release,2022,345:371-384.
［20］LYU Z,JIN L,GAO W,et al.Novel YOF-based theranostic agents with a cascade effect for NIR-Ⅱ fluorescence imaging and synergistic ttarvation/photodynamic therapy of orthotopic gliomas［J］.ACS Appl Mater Interfaces,2022,14(27):30523-30532.
［21］SUN R,LIU M,LU J,et al.Bacteria loaded with glucose polymer and photosensitive ICG silicon-nanoparticles for glioblastoma photothermal immunotherapy［J］.Nat Commun,2022,13(1):5127.
［22］HAMBURGER AW,SALMON SE.Primary bioassay of human tumor stem cells［J］.Science,1977,197(4302):461.
［23］JING H,WEIDENSTEINER C,REICHARDT W,et al.Imaging and selective elimination of glioblastoma stem cells with theranostic near-infrared-labeled CD133-specific antibodies［J］.Theranostics,2016,6(6):862-874.
［24］SINGH PK,SRIVASTAVA AK,DEV A,et al.1,3β-Glucan anchored,paclitaxel loaded chitosan nanocarrier endows enhanced hemocompatibility with efficient anti-glioblastoma stem cells therapy［J］.Carbohydr Polym,2018,180:365-375.
［25］WANG Z,LIANG P,HE X,et al.Etoposide loaded layered double hydroxide nanoparticles reversing chemoresistance and eradicating human glioma stem cells in vitro and in vivo［J］.Nanoscale,2018,10(27):13106-13121.
［26］MANJU CA,JEENA K,RAMACHANDRAN R,et al.Intracranially injectable multi-siRNA nanomedicine for the inhibition of glioma stem cells［J］.Neurooncol Adv,2021,3(1):vdab104.
［27］YOUNIS M,FAMING W,HONGYAN Z,et al.Iguratimod encapsulated PLGA-NPs improves therapeutic outcome in glioma,glioma stem-like cells and temozolomide resistant glioma cells［J］.Nanomedicine,2019,22:102101.
［28］KNAUER N,ARKHIPOVA V,LI G,et al.In vitro validation of the therapeutic potential of dendrimer-based nanoformulations against tumor stem cells［J］.Int J Mol Sci,2022,23(10):5691.
［29］LIU Y,ZHENG M,JIAO M,et al.Polymeric nanoparticle mediated inhibition of miR-21 with enhanced miR-124 expression for combinatorial glioblastoma therapy［J］.Biomaterials,2021,276:121036.
［30］KINOH H,QUADER S,SHIBASAKI H,et al.Translational nanomedicine boosts anti-PD1 therapy to eradicate orthotopic PTEN-negative glioblastoma［J］.ACS Nano,2020,14(8):10127-10140.
［31］ZHOU Y,GUO Y,CHEN L,et al.Co-delivery of phagocytosis checkpoint and STING agonist by a Trojan horse nanocapsule for orthotopic glioma immunotherapy［J］.Theranostics,2022,12(12):5488-5503.
［32］ZHANG J,CHEN C,LI A,et al.Immunostimulant hydrogel for the inhibition of malignant glioma relapse post-resection［J］.Nat Nanotechnol,2021,16(5):538-548.
［33］SHARMA R,LIAW K,SHARMA A,et al.Glycosylation of PAMAM dendrimers significantly improves tumor macrophage targeting and specificity in glioblastoma［J］.J Control Release,2021,337:179-192.
［34］QUADER S,LIU X,TOH K,et al.Supramolecularly enabled pH-triggered drug action at tumor microenvironment potentiates nanomedicine efficacy against glioblastoma［J］.Biomaterials,2021,267:120463.
［35］DOUSTI F,SOLEIMANBEIGI M,MIRIAN M,et al.Boron phenyl alanine targeted ionic liquid decorated chitosan nanoparticles for mitoxantrone delivery to glioma cell line［J］.Pharm Dev Technol,2021,26(8):899-909.
［36］CHAVARRIA V,ORTIZ-ISLAS E,SALAZAR A,et al.Lactate-loaded nanoparticles induce glioma cytotoxicity and increase the survival of rats bearing malignant glioma brain tumor［J/OL］.Pharmaceutics,2022,14(2):327［2022-02-29］.https://doi.org/10.3390/pharmaceutics14020327.
［37］DI FILIPPO LD,LOBATO DUARTE J,HOFSTATTER AZAMBUJA J.Glioblastoma multiforme targeted delivery of docetaxel using bevacizumab-modified nanostructured lipid carriers impair in vitro cell growth and in vivo tumor progression［J/OL］.Int J Pharm,2022,618:121682［2022-03-17］.https://doi.org/10.1016/j.ijpharm.2022.121682.
［38］UNNIKRISHNAN BS,PREETHI GU,SREELEKHA TT.A comprehensive study on 2D,3D and solid tumor environment to explore a multifunctional biogenic nanoconjugate［J］.Sci Rep,2021,11(1):8721.
［39］MALEKI H,HOSSEINI NAJAFABADI MR,WEBSTER TJ,et al.Effect of paclitaxel/etoposide co-loaded polymeric nanoparticles on tumor size and survival rate in a rat model of glioblastoma［J/OL］.Int J Pharm,2021,604:120722［2021-04-20］.https://doi.org/10.1016/j.ijpharm.2021.120722.
［40］LIU Y,ZHENG M,JIAO M,et al.Polymeric nanoparticle mediated inhibition of miR-21 with enhanced miR-124 expression for combinatorial glioblastoma therapy［J/OL］.Biomaterials,2021,276:121036［2021-07-20］.https://doi.org/10.1016/j.biomaterials.2021.121036.
［41］HWANG D,DISMUKE T,TIKUNOV A,et al.Poly(2-oxazoline) nanoparticle delivery enhances the therapeutic potential of vismodegib for medulloblastoma by improving CNS pharmacokinetics and reducing systemic toxicity［J/OL］.Nanomedicine,2021,32:102345［2020-11-28］.https://doi.org/10.1016/j.nano.2020.102345.
［42］KUMAR V,WANG Q,SETHI B,et al.Polymeric nanomedicine for overcoming resistance mechanisms in hedgehog and Myc-amplified medulloblastoma［J/OL］.Biomaterials,2021,278:121138［2021-09-29］.https://doi.org/10.1016/j.biomaterials.2021.121138.
［43］MIRZAEI S,MAHABADY MK.Small interfering RNA(siRNA) to target genes and molecular pathways in glioblastoma therapy:Current status with an emphasis on delivery systems［J/OL］.Life Sci,2021,275:119368［2021-03-16］.https:// doi:10.1016/j.lfs.2021.119368.
［44］JIANG T,QIAO Y,RUAN W,et al.Cation-free siRNA micelles as effective drug delivery platform and potent RNAi nanomedicines for glioblastoma therapy［J］.Adv Mater,2021,33(45):e2104779.
［45］REHMAN FU,LIU Y,YANG Q,et al.Heme Oxygenase-1 targeting exosomes for temozolomide resistant glioblastoma synergistic therapy［J］.J Control Release,2022,345:696-708.