|Table of Contents|

Research progress of application of graphene based nanomaterials in the diagnosis and treatment of breast cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2024 07
Page:
1370-1374
Research Field:
Publishing date:

Info

Title:
Research progress of application of graphene based nanomaterials in the diagnosis and treatment of breast cancer
Author(s):
ZHANG Bocheng1; WANG Shengtao2
1.Thyroid and Breast Surgery Department of Sanya Central Hospital (The Third People's Hospital of Hainan Province),Hainan Sanya 572000,China;2.Affiliated Foshan Maternity & Child Healthcare Hospital,Southern Medical University (Foshan Maternity & Child Healthcare Hospital),Guangdong Foshan 528000,China.
Keywords:
graphene; breast cancer; graphene oxide; multifunctional nanoparticles; molecular targeted therapy; combined modality therapy
PACS:
R737.9
DOI:
10.3969/j.issn.1672-4992.2024.07.034
Abstract:
Breast cancer is the most common malignant tumor in women,and its incidence rate is increasing year by year.Traditional diagnosis and treatment methods are still insufficient,so it is urgent need to explore new diagnosis and treatment strategies.Graphene based nanomaterials (GBNs) are promising drug carriers with the advantages of target selectivity,photoluminescence,easy functionalization,chemical sensitization and high drug loading.This paper first summarized the biological characteristics of GBNs in cancer treatment,and then focused on the application of GBNs in the diagnosis and treatment of breast cancer,including chemotherapy,phototherapy,targeted therapy,early diagnosis and tumor imaging,as a platform for combined modality therapy and modification strategies.The advantages of GBNs in reducing toxicity and increasing efficiency,multi-drug delivery,biosensing,molecular imaging and combination therapy were emphasized.Finally,the problems and challenges of GBNs in the field of breastcancer diagnosis and treatment were clarified,aiming to point out the direction for researchers and provide new ideas.

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Memo

Memo:
2022年度广东省基础与应用基础研究基金联合基金项目（编号：2022A1515110270）；海南省“南海新星”医疗卫生人才平台项目资助（编号：28号）
Last Update: 2024-02-29