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Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:

2024 07

Page:

1340-1343

Research Field:

Publishing date:

Info

Title:

Advances in clinical features and driver gene mutation of young patients with lung adenocarcinoma

Author(s):

SUN Zhuochen¹; TIAN Feng²; WEI Jun¹

1.Department of Thoracic Surgery,Air Force 986 Hospital of Air Force Medical University,Shaanxi Xi'an 710054,China;2.Department of Thoracic Surgery,Tangdu Hospital of Air Force Medical University,Shaanxi Xi'an 710038,China.

Keywords:

young lung adenocarcinoma; pathological features; driver gene mutations

PACS:

R734.2

DOI:

10.3969/j.issn.1672-4992.2024.07.028

Abstract:

In recent years,with the use of low-dose CT (LDCT) in lung cancer screening,increasing number of young patients are being diagnosed with lung cancer.Although the proportion of young non-small cell lung cancer (NSCLC) patients (¡Ü45 years old) is low,it has unique clinicopathological features and genetic mutation loci.As the most common pathological type of NSCLC in young patients,lung adenocarcinoma has less research on its oncogenic genetic alterations (GAs) and clinical features.With the concept of individualized treatment of lung cancer,its population studies are gradually gaining attention.Therefore,it is of great clinical importance to study adenocarcinoma of the lung in young adults.In this paper,we review the trends,pathological features and driver mutations in young patients with lung adenocarcinoma.

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Memo

Memo:

National Natural Science Foundation of China£¨No.81770068£©;¹ú¼Ò×ÔÈ»¿Æѧ»ù½ð×ÊÖúÏîÄ¿£¨±àºÅ£º81770068£©

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Last Update: 2024-02-29