|Table of Contents|

Analysis of poor wound healing after modified radical mastectomy in breast cancer patients complicated with hypertension

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

2015 13
Research Field:
Publishing date:


Analysis of poor wound healing after modified radical mastectomy in breast cancer patients complicated with hypertension
Zhang PingMa TaoSong WeiDing YunLu Xiaowei
Wuxi Hospital for Maternal and Child Health Care,Jiangsu Wuxi 214002,China.
breast cancerhypertensionmodified radical mastectomywound healing
Objective:To analyze the reasons for poor wound healing after modified radical mastectomy (MRM) in breast cancer patients complicated with hypertension,and to investigate methods to promote the wound healing.Methods:Clinical data of 76 breast cancer patients was randomly collected who received modified radical mastectomy in our hospital from August 2012 to August 2014.76 breast cancer patients were divided into two groups,the control group has 37 patients without any complication,and the observation group 39 patients who were complicated by hypertension.Wound healing was compared between these two groups.Results:Average days of drainage was 19.1±7.0 in control group,while 29.3±18.3 days in the observation group with more drainage.Compared with the control group,wound healing in observation group was obviously delayed (P<0.01).Conclusion:The wounds of breast cancer patients complicated with hypertension healed slowly after MRM.The maintenance of stable blood pressure and proper intra-operative and post-operative medical nursing will promote the wound healing effectively and greatly improve the life quality of patients after MRM.


[1]Hao J,Zhao P,Chen WQ.Chinese cancer registry annual report[M].Beijing:Military Med Scie Press,2012:26.[赫捷,赵平,陈万青.中国肿瘤登记年报[M].北京:军事医学科学出版社,2012:26.]
[2]Zhou H,Yang L.Assessment and treatment of blood pressure in anesthesia management of hypertensive patients[J].Healthmust-readmagazine,2013,12(6):240-241.[周华,杨柳.高血压病人手术麻醉管理中血压的评估和处理[J].健康必读旬刊,2013,12(6):240-241.]
[3]Khan H,Khan AU,Khan MA,et al.Association between hypertension and seroma formation in patients after modified radical mastectomy for carcinoma breast[J].Kyber J Med Scie,2013,6(2):307-310.
[4]D Sanders Honorary,Lecturer R.How important is peri-operative hypertension[J]?Anaha,2014,69(9):948-953.
[5]Young A,McNaught CE.The physiology of wound healing[J].Surgery(Oxford),2011,29(10):475-479.
[6]Gourevitch D,Kossenkov AV,Zhang Y.Inflammation and its correlates in regenerative wound healing:an alternate perspective[J].Advances in Wound Care,2014,3(9):592-603.
[7]Tu Z,Li Z.Prevention and treatment of skin flap necrosis of 48 breast cancer patients after modified radical mastectomy[J].Chin Manipulation & Rehabilition Med,2012,3(8):105.[涂智,李柱.防治乳腺癌改良根治术后皮瓣坏死48例临床研究[J].按摩与康复医学,2012,3(8):105.]
[8]Sakkary MA.The value of mastectomy flap fixation in reducing fluid drainage and seroma formation in breast cancer patients[J].World J Surg Oncol,2012,10(6):8-11.
[9]Zielinski J,Jaworski R,Irga N,et al.Analysis of selected factors influencing seroma formation in breast cancer patients undergoing mastectomy[J].Arch Med Sci,2013,9(1):86-92.
[10]Xue DQ,Qian C,Yang L.Risk factors for surgical site infections after breast surgery:a systematic review and meta-analysis[J].Eur J Surg Oncol(EJSO),2012,38(5):375-381.
[11]Chand N,Aertssen AMG,Royle GT.Axillary"Exclusion"-A successful technique for reducing seroma formation after mastectomy and axillary dissection[J].Advances in Breast Cancer Res,2013,6(2):307-310.
[12]Jin X,Wang CH,Chen WX.Clinical nursing experience after modified radical mastectomy of Breast Cancer[J].Guide of China Med,2010,8(20):152-153.[金霞,王春红,陈伟霞.乳腺癌改良根治术后的临床护理体会[J].中国医药指南,2010,8(20):152-153.]


Last Update: 2015-05-29