|Table of Contents|

The biological function of PDCD10 gene and its research progress in tumor

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2025 04
Page:
683-689
Research Field:
Publishing date:

Info

Title:
The biological function of PDCD10 gene and its research progress in tumor
Author(s):
DING PengCHEN XuLIU SulaiSUN Bo
Department of Hepatobiliary Surgery,Hunan Provincial People's Hospital(the First Affiliated Hospital of Hunan Normal University),Hunan Changsha 410002,China.
Keywords:
programmed cell death 10programmed cell deathapoptosissignal transmissiontumor
PACS:
R730
DOI:
10.3969/j.issn.1672-4992.2025.04.021
Abstract:
Programmed cell death 10 (PDCD10) gene is closely related to programmed cell death as it is the third important gene that causes cerebral cavernous malformation (CCM),hence also known as CCM3.PDCD10 gene encodes an ankyrin,which can bind different target proteins to participate in a variety of intracellular signal transduction pathways,and is closely related to cell proliferation,apoptosis,migration and angiogenesis.More and more evidence shows that the expression of PDCD10 is dysregulated in a variety of malignant tumors and is involved in the occurrence and development of malignant tumors.It is of great clinical significance to reveal the mechanism of action of PDCD10 in tumors,which is helpful for the early diagnosis and treatment of diseases and prognosis,as well as to explore new therapeutic targets in cancer prevention and treatment.

References:

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Memo

Memo:
National Natural Science Foundation of China(No.82303186);国家自然科学基金青年基金项目(编号:82303186)
Last Update: 1900-01-01