|Table of Contents|

Dosimetry study based on tangential arc radiotherapy at the medial margin of mammary gland after radical resection of left breast cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2025 04
Page:
590-597
Research Field:
Publishing date:

Info

Title:
Dosimetry study based on tangential arc radiotherapy at the medial margin of mammary gland after radical resection of left breast cancer
Author(s):
LI Han; ZHAO Biao; YUAN Meifang; LI Jing; ZHU Cencheng; YANG Yi
Department of Radiotherapy,Yunnan Cancer Hospital，the Third Affiliated Hospital of Kunming Medical University,Peking University Cancer Hospital Yunnan Hospital,Yunnan Kunming 650118,China.
Keywords:
medial margin tangent; VMAT; left breast cancer; radical mastectomy; dosimetry
PACS:
R737.9
DOI:
10.3969/j.issn.1672-4992.2025.04.007
Abstract:
Objective:To explore the dosimetric difference between medial margin tangential arc and conventional tangential arc in VMAT after radical left mastectomy,provide reference for clinical optimization planning.Methods:36 patients who received radiotherapy after radical mastectomy in our hospital from January 2022 to June 2024 were retrospectively selected.VMAT plans were designed for each patient in two groups:Medial margin tangent (MMTiso) and conventional tangential arc (CTAiso).Target conformity index (CI),homogeneity index (HI),D2,D50,D98 and organ at risk of two groups of plans were collected.The dosimetric differences in planning target volume and organ at risk between the two groups were compared.Results:D98,D2,CI and HI in MMTiso group were better than CTAiso group,the difference was statistically significant (P＜0.05）.The results of left lung （Dmean，V30，V20，V5）,heart（Dmean，V5）and spinal cord（D2） in MMTiso group were lower than those in CTAiso group.The left lung V20 and V5 were (21.02±3.49)% vs (24.39±3.71）%,（48.61±3.64）% vs （53.75±4.19）%,the difference was statistically significant (P＜0.05),heart Dmean and V5 were （579.24±161.14）cGy vs (636.21±168.19)cGy,(22.92±6.52)% vs (25.81±6.79)%,the difference was statistically significant (P＜0.05).Conclusion:Both plans meet clinical dose requirements.The irradiation mode of medial margin tangent improves the CI and HI of the target area,reduces the dose of left lung (Dmean,V30,V20,V5),heart (Dmean,V5) and spinal cord（D2），to achieve the greater dose benefits for vital organs such as the heart and lungs.Taken together,the medial tangential arc is more advantageous in VMAT radiotherapy planning after radical mastectomy.

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Memo

Memo:
National Natural Science Foundation of China(No.32360114）；国家自然科学基金资助项目（编号：32360114）
Last Update: 1900-01-01