|Table of Contents|

Research progress on the effects of brown adipose tissue-regulated energy metabolism on tumor

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2024 21
Page:
4200-4205
Research Field:
Publishing date:

Info

Title:
Research progress on the effects of brown adipose tissue-regulated energy metabolism on tumor
Author(s):
PEI Rongrong12CHEN Xiaoqi1ZHAO Qing1ZHANG Chuanlei1WANG Xinting1YUAN Changwei1YANG Fangming1CHEN Xinju1
1.Henan University of Traditional Chinese Medicine,Henan Zhengzhou 450046,China;2.Department of Gastroenterology,the First Affiliated Hospital of Henan University of Traditional Chinese Medicine,Henan Zhengzhou 450000,China.
Keywords:
brown adipose tissuetumor metabolismresearch progress
PACS:
R730
DOI:
10.3969/j.issn.1672-4992.2024.21.034
Abstract:
Reprogramming of energy metabolism is an important biological feature of tumor cells,which provides energy for tumor growth and proliferation through metabolic methods such as abnormal glycolysis and enhanced fatty acid synthesis.Brown adipose activation uptake of glucose and free fatty acids creates metabolic competition in tumor growth and proliferation,which inhibits tumor growth but accelerates malignant progression during periods of hypermetabolic malignancy.This article reviews the role of brown adipose tissue in energy metabolism and its effects on tumors,with a view to providing new ideas for the treatment of malignant tumors or cachexia.

References:

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河南省自然科学基金项目(编号:242300421298)
Last Update: 2024-09-30