|Table of Contents|

Clinical and pathological analysis of 5 patients with thyroid eosinophilic carcinoma

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2024 21
Page:
4066-4070
Research Field:
Publishing date:

Info

Title:
Clinical and pathological analysis of 5 patients with thyroid eosinophilic carcinoma
Author(s):
WANG Liping; ZHONG Guodong; LIN Shengming; WEI Lin; LIN Jianlong
Department of Pathology,the Second People’s Hospital Affiliated to Fujian University of Chinese Medicine,Fujian Fuzhou 350001,China.
Keywords:
thyroid oncocytic cell carcinoma; prognosis; differential diagnosis
PACS:
R736.1
DOI:
10.3969/j.issn.1672-4992.2024.21.009
Abstract:
Objective:To investigate the clinicopathological features,diagnosis,differential diagnosis and prognosis of thyroid oncocytic cell carcinoma (OCA).Methods:The clinicopathological data of 5 cases of thyroid OCA were collected,and the pathologic features and prognostic relationship were analyzed,and the relevant literature were reviewed.Results:Among the 5 patients,there were 3 females and 2 males,with ages ranging from 42 to 70 years and an average age of 53.4 years.The maximum diameter of tumor was 2~7.5 cm,with an average of 4.9 cm.Microscopically,all tumors showed fibrous capsule,3 cases showed vascular invasion,of which 2 cases also had capsule invasion,and the other 2 cases only showed capsule invasion.The cytoplasm of the tumor cells is abundant,oncocytic,granular,and nucleolus was visible.No nuclear features of papillary thyroid carcinoma (PTC) were found,the mitotic images were rare and neoplastic necrosis was not observed.No recurrence or metastasis disease was found in the 5 patients during the follow up for 9~41 months.Conclusion:Thyroid OCA is an aggressive tumor with low incidence,high risk of metastasis and poor prognosis.It has its unique pathologic features and molecular changes,which should be distinguished from other thyroid tumors with oncocytic degeneration.

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Memo:
福建省中青年教师教育科研项目（科技类）（编号：JAT220121）
Last Update: 2024-09-30