|Table of Contents|

Analysis of accuracy and influencing factors of digital mammary tomography in measuring the size of invasive ductal breast cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2024 19
Page:
3731-3737
Research Field:
Publishing date:

Info

Title:
Analysis of accuracy and influencing factors of digital mammary tomography in measuring the size of invasive ductal breast cancer
Author(s):
LI Hongen; LI Yuelong; HUANG Yubin; ZENG Yihui; ZHANG Liang; MEI Shiwei
Department of Radiology,Guangdong Province Hospital for Women and Children Healthcare,Guangdong Guangzhou 511400,China.
Keywords:
digital breast tomography; lesion size; invasive ductal carcinoma of breast; influencing factor
PACS:
R737.9
DOI:
10.3969/j.issn.1672-4992.2024.19.018
Abstract:
Objective:To investigate the accuracy of digital breast tomosynthesis (DBT) in evaluating the lesion size of invasive mammary ductal carcinoma (IDC),and analyze the influencing factors.Methods:The clinical data of 145 patients diagnosed with IDC by surgical pathology in our hospital from March 2019 to August 2022 were retrospectively analyzed.All patients underwent DBT examination before surgery.Spearman correlation analysis and Bland-Altman chart were used to compare the correlation and consistency of DBT in predicting IDC lesion size.Multivariate Logistic regression was used to analyze the predictive factors of inaccurate DBT measurement of IDC lesion size.Results:The median (interquartile distance) of focal size measured by DBT and pathology were 2.1(1.5,2.8) cm and 2.5(2.0,3.0) cm,respectively.The consistent rate of lesion size measured by DBT was 75.86%(110/145),underestimation 21.38%(31/145) and overestimation 2.76%(4/145).Spearman correlation analysis showed that DBT was moderately positively correlated with pathologically measured IDC lesion size (r=0.575,P＜0.001).Bland-Altman analysis showed that the DBT examination slightly underestimated the lesion size compared with the pathological gold standard,with a mean difference of -0.408 cm and 95%CI of -0.559~-0.258.Multivariate Logistic regression analysis showed that pathological measurement size >2 cm and irregular mass shape were independent risk factors for inaccurate DBT measurement of IDC lesion size (OR=8.110,95%CI 2.077 ~ 31.672,P=0.003).OR=0.301,95%CI was 0.113 ~ 0.798,P=0.016).Conclusion:The size of IDC lesions measured by DBT showed a moderate correlation with the pathological measurements,and the consistency rate of IDC lesion size measurements was high,which could be used as a basis for predicting the size of IDC lesions before surgery,but there were still cases of underestimating the size of lesions.It is more likely that the lesion size of IDC with pathological measurement size >2 cm and irregular tumor shape will be inaccurate.

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Last Update: 2024-08-30