[1] BRAY F,LAVERSANNE M,SUNG H,et al.Global cancer statistics 2022:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J].CA Cancer J Clin,2024,74(3):229-263.
[2] SEGURA A,PARDDO J,JARA C,et al.An epidemiological evaluation of the prevalence of malnutrition in Spanish patients with locally advanced or metastatic cancer[J].Clin Nutr,2005,24(5):801-814.
[3] 宋春花,王昆华,郭增清,等.中国常见恶性肿瘤患者营养状况调查[J].中国科学:生命科学,2020,50(12):1437-1452.
SONG CH,WANG KH,GUO ZQ,et al.Investigation of nutritional status in Chinese patients with common cancer[J].SCIENTIA SINICA Vitae,2020,50(12):1437-1452.
[4] 于恺英,刘俐惠,石汉平.肿瘤营养相关状况诊断标准[J].肿瘤代谢与营养电子杂志,2020,7(01):1-6.
YU KY,LIU LH,SHI HP.Diagnostic criteria of cancer nutrition related status[J].Electronic Jourmal of Metabolism and Nutrition of Cancer,2020,7(01):1-6.
[5] MUSCARITOLI M,CORSARO E,MOLFINO A.Awareness of cancer-related malnutrition and its management:Analysis of the results from a survey conducted among medical oncologists[J].Front Oncol,2021,11:682999.
[6] BOSAEUS L.Dietary intake,resting energy expenditure,weight loss and survival in cancer patients[J].International Research Conference on Food,Nutrition & Cancer,2002,132(suppl_11):3465S-3466S.
[7]VAZEILLE C,JOUINOT A,DURAND JP,et al.Relation between hypermetabolism,cachexia,and survival in cancer patients:a prospective study in 390 cancer patients before initiation of anticancer therapy[J].Am J Clin Nutr,2017,105(5):1139-1147.
[8] 石汉平,于恺英,丛明华,等.恶性肿瘤营养不良的特征[J].肿瘤代谢与营养电子杂志,2020,7(03):276-282.
SHI HP,YU KY,CONG MH,et al.Characteristics of malnutrition in malignant cancer patients[J].Electronic Jourmal of Metabolism and Nutrition of Cancer,2020,7(03):276-282.
[9] 孙学梦,刘芳远,苏丽娅.代谢重编程在恶性肿瘤中作用的研究进展[J].中国肿瘤生物治疗杂志,2023,30(05):432-437.
SUN XM,LIU FY,SU LY.The review of the function of metabolic reprogramming in the malignant tumor[J].Chinese Journal of Cancer Biotherapy,2023,30(05):432-437.
[10]NISHIKAWA H,GOTO M,FUKUNISHI S,et al.Cancer cachexia:Its mechanism and clinical significance[J].Int J Mol Sci,2021,22(16):8491.
[11] SUN X,FENG X,WU X,et al.Fat wasting is damaging:Role of adipose tissue in cancer-associated cachexia[J].Front Cell Dev Biol,2020,8:33.
[12] DIAKOS CI,CHARLES KA,MCMILLAN DC,et al.Cancer-related inflammation and treatment effectiveness[J].Lancet Oncol,2014,15(11):e493-503.
[13] GRETEN FR,GRIVENNIKOV SI.Inflammation and cancer:Triggers,mechanisms,and consequences[J].Immunity,2019,51(1):27-41.
[14] BALKWILL F,MANTOVANI A.Inflammation and cancer:back to Virchow[J].Lancet,2001,357(9255):539-545.
[15] 文粟,刘汇泉,于世英.癌性厌食发病机制和临床诊疗的研究进展[J].中国肿瘤临床,2020,47(19):1013-1018.
WEN S,LIU HQ,YU SY.Review of pathogenesis,clinical diagnosis and treatment of cancer-related anorexia[J].Chinese Journal of Clinical Oncology,2020,47(19):1013-1018.
[16] 冯彩云,于恺英,石汉平.营养影响症状[J].肿瘤代谢与营养电子杂志,2023,10(02):172-176.
FENG CY,YU KY,SHI HP.Nutrition impact symptoms[J].Electronic Jourmal of Metabolism and Nutrition of Cancer,2023,10(02):172-176.
[17] NG HS,RODER D,KOCZWARA B,et al.Comorbidity,physical and mental health among cancer patients and survivors:An Australian population-based study[J].Asia-Pacific Journal of Clinical Oncology,2018,14(2):E181-E192.
[18] WONG SH,KWONG TNY,WU CY,et al.Clinical applications of gut microbiota in cancer biology[J].Semin Cancer Biol,2019,55:28-36.
[19] BAUER PV,HAMR SC,DUCA FA.Regulation of energy balance by a gut-brain axis and involvement of the gut microbiota[J].Cell Mol Life Sci,2016,73(4):737-755.
[20] DONOHOED R,WALI A,BRYLAWSKI BP,et al.Microbial regulation of glucose metabolism and cell-cycle progression in mammalian colonocytes[J].PLoS One,2012,7(9):e46589.
[21] CSCO肿瘤营养治疗专家委员会.恶性肿瘤患者的营养治疗专家共识[J].临床肿瘤学杂志,2012,17(01):59-73.
CSCO Expert Committee on Nutritional Therapy in Oncology.Expert consensus on nutritional therapy for patients with cancer[J].Journal of Cancer Research and Clinical Oncology,2012,17(01):59-73.
[22] CEDERHOLM T,BOSAEUS I,BARAZZONI R,et al.Diagnostic criteria for malnutrition-an ESPEN consensus statement[J].Clin Nutr,2015,34(3):335-340.
[23] CEDERHOLM T,JENSEN GL,CORREIA M,et al.GLIM criteria for the diagnosis of malnutrition-a consensus report from the global clinical nutrition community[J].Clin Nutr,2019,38(1):1-9.
[24] XU J,JIE Y,SUN Y,et al.Association of global leadership initiative on malnutrition with survival outcomes in patients with cancer:A systematic review and meta-analysis[J].Clin Nutr,2022,41(9):1874-1880.
[25]CSCO肿瘤营养治疗专家委员会.2021CSCO恶性肿瘤患者营养治疗指南[M].北京:人民卫生出版社,2021:13-25.
CSCO Expert Committee on Nutritional Therapy in Oncology.2021CSCO nutrition in cancer patients[M].Beijing:People's Medical Publishment House,2021:13-25.
[26] POULIA KA,KLEK S,DOUNDOULAKIS I,et al.The two most popular malnutrition screening tools in the light of the new ESPEN consensus definition of the diagnostic criteria for malnutrition[J].Clin Nutr,2017,36(4):1130-1135.
[27] ZHANG Z,WAN Z,ZHU Y,et al.Prevalence of malnutrition comparing NRS2002,MUST,and PG-SGA with the GLIM criteria in adults with cancer:A multi-center study[J].Nutrition,2021,83:111072.
[28] 刘杏,潘丽,李苏宜.肿瘤患者营养诊断临床(建议)路径[J].中国临床研究,2023,36(05):738-740+745.
LIU X,PAN L,LI SY.Clinical (recommended) pathway for nutritional diagnosis in oncology patients[J].Chinese Journal of Clinical Research,2023,36(05):738-740+745.
[29] 石汉平,丛明华,陈伟.再论营养不良的三级诊断[J].中国医学前沿杂志(电子版),2020,12(01):1-7+159.
SHI HP,CONG MH,CHEN W.Rethinking for three-level diagnosis of malnutrition[J].Chinese Journal of the Frontiers of Medical Science(Electronic Version),2020,12(01):1-7+159.
[30] RONDEL A,LANGIUS JAE,DE VAN DER SCHUEREN MAE,et al.The new ESPEN diagnostic criteria for malnutrition predict overall survival in hospitalised patients[J].Clin Nutr,2018,37(1):163-168.
[31] 石汉平,许红霞,李苏宜,等.营养不良的五阶梯治疗[J].肿瘤代谢与营养电子杂志,2015,2(01):29-33.
SHI HP,XU HX,LI SY,et al.Five-step treatment of malnutrition[J].Electronic Jourmal of Metabolism and Nutrition of Cancer,2015,2(01):29-33.
[32] 蔡泽君,谢浩芬,徐琴鸿,等.加速康复外科背景下的早期肠内营养与肠外营养对有营养风险胃癌患者术后临床结局的影响[J].中华临床营养杂志,2019,27(5):281-286.
CAI ZJ,XIE HF,XU QH,et al.Effect of early enteral nutrition and parenteral nutrition on the postoperative outcomes of patients with gastric cancer and nutritional riskin enhanced recovery after surgery[J].Chinese Journal of Clinical Nutrition,2019,27(5):281-286.
[33] 彭启旺,邓浩.肠内营养支持对根治性胃癌术后胃肠功能、营养状态和应激炎性反应影响[J].临床外科杂志,2021,29(05):445-448.
PENG QW,DENG H.The effect of enteral nutrition support on gastrointestinal function,nutritional status and stress inflammatory response after radical gastric cancer surgery[J].Journal of Clinical Surgery,2021,29(05):445-448.
[34] COTOGNI P,MONGE T,PASSERA R,et al.Clinical characteristics and predictive factors of survival of 761 cancer patients on home parenteral nutrition:A prospective,cohort study[J].Cancer Med,2020,9(13):4686-4698.
[35] 丛明华.肠外营养安全性管理中国专家共识[J].肿瘤代谢与营养电子杂志,2021,8(05):495-502.
CONG MH.Chinese expert consensus on the safety of parenteral nutrition[J].Electronic Jourmal of Metabolism and Nutrition of Cancer,2021,8(05):495-502.
[36] CHOW R,BRUERA E,ARENDS J,et al.Correction to:Enteral and parenteral nutrition in cancer patients,a comparison of complication rates:an updated systematic review and (cumulative) meta-analysis[J].Support Care Cancer,2020,28(3):1011-1029.
[37] LIU CA,LIU T,LI HC,et al.Nutrition impact symptoms:Noteworthy prognostic indicators for lung cancer[J].Clinical Nutrition,2023,42(4):550-558.
[38] JIN SL,LU Q,SUN Y,et al.Nutrition impact symptoms and weight loss in head and neck cancer during radiotherapy:a longitudinal study[J].Bmj Supportive & Palliative Care,2021,11(1):17-24.
[39] SYDES MR,SPEARS MR,MASON MD,et al.Adding abiraterone or docetaxel to long-term hormone therapy for prostate cancer:directly randomised data from the STAMPEDE multi-arm,multi-stage platform protocol[J].Ann Oncol,2018,29(5):1235-1248.
[40] 冯宇.《金匮要略》虚劳篇对中医诊治肿瘤恶液质的启示[J].中华保健医学杂志,2022,24(03):257-258.
FENG Y.Implications of the "Jin Gui Yao Lue" chapter on deficiency and labour for Chinese medicine in the diagnosis and treatment of cancer cachexia[J].Chinese Journal of Health Care and Medicine,2022,24(03):257-258.
[41] 程海波,吴勉华.周仲瑛教授“癌毒”学术思想探析[J].中华中医药杂志,2010,25(06):866-869.
CHENG HB,WU MH.Discussion on academic thought of Professor ZHOU Zhong-ying about cancerous toxin[J].China Journal of Traditional Chinese Medicine and Pharmacy,2010,25(06):866-869.
[42] 王冰梅,马建,李敬孝.运用“甘温扶阳、脾肾为先”法治疗虚劳病的应用验案[J].环球中医药,2020,13(12):2114-2117.
WANG BM,MA J,LI JX.A case of applying the method of "GanWenFuYang,PiShenWeiXian" in the treatment of deficiency labour diseases[J].Global Traditional Chinese Medicine,2020,13(12):2114-2117.
[43] 朱鹏辉.运中固肾法在肝癌恶病质前期治疗中联合应用的临床观察[D].南昌:江西中医药大学,2022.
ZHU PH.Clinical observation on the combined application of the YunZhongGuShen method in the early treatment of hepatocellular carcinoma cachexia[D].Nanchang:Jiangxi University of Chinese Medicine,2022.
[44] 於悦,刘钧.健脾益肾汤结合肠内营养粉对肿瘤患者营养状况的影响[J].现代中西医结合杂志,2015,24(26):2939-2940.
YU Y,LIU J.Effect of JianPiYiShen Decoction combined with enteral nutrition powder on the nutritional status of cancer patients[J].Modern Journal of Integrated Traditional Chinese and Western Medicine,2015,24(26):2939-2940.
[45] 张梦雪,邹玺,吴坚,等.刘沈林教授治疗癌症恶病质经验[J].湖南中医药大学学报,2022,42(07):1199-1202.
ZHANG MX,ZOU X,WU J,et al.Professor LIU Shenlin's experience in treating cancer cachexia[J].Journal of Hunan University of Chinese Medicine,2022,42(07):1199-1202.
[46] 张玉红.和胃汤治疗癌症食欲不振恶病质综合征的临床观察[D].北京:北京中医药大学,2015.
ZHANG YH.Clinical observation on the treatment of cancer cachexia syndrome with loss of appetite with HeWei Decoction[D].Beijing:Beijing University of Chinese Medicine,2015.
[47] 孙艳,涂建龙,李子木,等.健脾养胃膏联合甲地孕酮治疗中晚期胃癌伴恶病质患者的临床疗效观察[J].中国中医药科技,2022,29(03):412-414.
SUN Y,TU JL,LI ZM,et al.Clinical observation on curative effect of advanced gastric cancer cachexia treated with Jianpi Yangwei Ointment combined with megestrol acetate[J].Chinese Journal of Traditional Medical Science and Technology,2022,29(03):412-414.
[48] 田智敏.参苓白术散对胰腺癌营养状况的改善及胰腺癌与肠道菌群和免疫的关系研究[D].上海:上海中医药大学,2019.
TIAN ZM.Improvement of nutritional status of pancreatic cancer and the relationship between pancreatic cancer and intestinal flora and immunity by ShenLingBaiZhu Decoction[D].Shanghai:Shanghai University of Chinese Medicine,2019.
[49] 梁芳,李朝衡,孙珏,等.四君子汤对肺癌恶病质小鼠骨骼肌萎缩及部分炎症细胞因子的影响[J].辽宁中医杂志,2012,39(07):1263-1265.
LIANG F,LI CH,SUN J,et al.Effect of Sijunzi Decoction on skeletal muscle atrophy and some inflammatory cytokines in lung cancer cachexia mice[J].Liaoning Journal of Traditional Chinese Medicine,2012,39(07):1263-1265.
[50] 杨振江,李佩聪,李琦.从调和肝脾治疗肿瘤恶液质初探[J].光明中医,2022,37(11):1929-1931.
YANG ZJ,LI PC,LI Q.A discussion of the treatment of cancer cachexia from TiaoHeGanPi[J].GUANGMING Journal of Chinese Medicine,2022,37(11):1929-1931.
[51] 王鹂.加味香砂归芍六君汤治疗癌症食欲不振/恶病质综合征的临床研究[D].南京:南京中医药大学,2017.
WANG L.Clinical study on the treatment of loss of appetite/malignant syndrome in cancer by XiangShaGuiShaoLiuJun Decoction PLUS[D].Nanjing:Nanjing University of Chinese Medicine,2017.
[52] 银赟,魏琪.基于癌毒病机理论探讨癌症恶病质辨治[J].中医临床研究,2022,14(01):60-62.
YIN Y,WEI Q.Discussion on the differentiation and treatment of cancer cachexia based on the theory of cancer toxin pathogenesis[J].Clinical Journal of Chinese Medicine,2022,14(01):60-62.
[53] 何国平,周培,赵轩竹,等.基于“干血劳”理论探讨活血化瘀法在癌症恶病质中应用的研究进展[J].中国中西医结合外科杂志,2021,27(05):799-804.
HE GP,ZHOU P,ZHAO XZ,et al.Review of the method of HuoXueHuaYu in cancer cachexia based on the theory of "GanXueLao"[J].Chinese Journal of Surgery of Integrated Traditional and Western Medicine,2021,27(05):799-804.
[54] 李克雄.扶正消积方治疗肿瘤恶液质的临床研究[D].长沙:湖南中医药大学,2021.
LI KX.Clinical study on the treatment of cancer cachexia by FuZhengXiaoJi Decoction[D].Changsha:HuNan University of Chinese Medicine,2021.
[55] 高震,杨静,贺雪黛,等.“消癌解毒方”对晚期肿瘤恶液质患者生活质量及外周血IL-6、TNF-α的影响-附30例临床资料[J].江苏中医药,2020,52(12):22-25.
GAO Z,YANG J,HE XD,et al.Effects of XiaoAiJieDu Decoction on quality of life and peripheral blood IL-6 and TNF-alpha in patients with advanced tumour malignant stasis-with clinical data of 30 cases[J].Jiangsu Journal of Traditional Chinese Medicine,2020,52(12):22-25.
[56] 王文苹,欧阳兵,吴智春,等.保元解毒汤改善癌性恶病质模型小鼠骨骼肌萎缩的实验研究[J].山东中医药大学学报,2013,37(05):423-425.
WANG WP,OUYANG B,WU ZC,et al.Experimental study of Baoyuan Jiedu decoction on gastrocnemius muscle atrophy of cancer cachexia model mice[J].Journal of Shandong University of Traditional Chinese Medicine,2013,37(05):423-425.
[57] 石汉平.营养治疗是肿瘤的一线治疗[J].临床药物治疗杂志,2019,17(04):20-25.
SHI HP.Nutrition therapy is the first-line therapy for cancer[J].Clinical Medication Journal,2019,17(04):20-25.