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Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:

2024 17

Page:

3347-3354

Research Field:

Publishing date:

Info

Title:

Biological function of HOXC8 and the progress of its role in digestive tract tumors

Author(s):

CHEN Qi¹; 2; LIU Sulai¹; 2; YI Weimin¹; 2

1.Department of Hepatobiliary Surgery,Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University,Hunan Changsha 410005,China;2.The Center Laboratory of Hunan Provincial People's Hospital,Hunan Changsha 410005,China.

Keywords:

HOXC8; transcription factors; biological functions; digestive tract tumors

PACS:

R735

DOI:

10.3969/j.issn.1672-4992.2024.17.030

Abstract:

The homeobox gene C8 (HOXC8),one of the members of the homeobox family,is a highly conservative transcription factor,which is widespread among vertebrates species including humans.HOXC8 is involved in many biological processes by specifically regulating the transcription of its target genes.In recent years,several researches indicate that the abnormal expression of HOXC8 is associated with the occurrence and development of various tumors.Thus,this paper will review the main biological functions and the role of HOXC8 in tumors or disease of digestive tract,aiming to providetheoretical basis for a new therapeutic target of tumors or disease of digestive system.

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Memo

Memo:

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Common functions

Last Update: 2024-07-31