|Table of Contents|

Ovarian malignant PEComa：A case report and review of the literature

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2024 17
Page:
3280-3285
Research Field:
Publishing date:

Info

Title:
Ovarian malignant PEComa：A case report and review of the literature
Author(s):
JIANG Mengfan1; 2; QIAN Jinfeng2
1.Hai'an Hosptital of Traditional Chinese Medicine,Jiangsu Nantong 226600,China;2.The First People's Hospital of Nantong,Jiangsu Nantong 226014,China.
Keywords:
ovarian tumor; perivascular epithelioid tumor; pathological diagnosis; differential diagnosis
PACS:
R737.31
DOI:
10.3969/j.issn.1672-4992.2024.17.019
Abstract:
Objective:To investigate the clinicopathological features,diagnosis,differential diagnosis,treatment and prognosis of primary malignant perivascular epithelioid cell tumor(PEComa) in ovary.Methods:One case of primary malignant PEComa of the ovary was analyzed by conventional pathology and immunohistochemical markers and literature review.Results:The tumor consisted of epithelioid to spindle-shaped cells,diffuse sheet-like growth,some areas of tumor cells were seen to surround the blood vessels in a radial arrangement,the tumor cell cytoplasm was translucent or pale eosinophilic red,pigmentation was seen,and necrosis and nuclear schizophrenia were seen.Immunohistochemistry：HMB45(+),Melan-A(+),TFE3(+),Ki-67(index <10%).Conclusion:Primary malignant PEComa of the ovary is a rare group of mesenchymal tumors expressing melanin markers and smooth muscle markers,with atypical clinical symptoms,histological morphology and immunomarkers are of great value in diagnosis and differential diagnosis,postoperative imaging follow-up is very important,and immunotherapy and radiation therapy are still worth exploring.

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Last Update: 2024-07-31