|Table of Contents|

Application progress of circulating tumor DNA in early diagnosis of gastric cancer and colorectal cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2024 15
Page:
2915-2920
Research Field:
Publishing date:

Info

Title:
Application progress of circulating tumor DNA in early diagnosis of gastric cancer and colorectal cancer
Author(s):
SHAN YifanDAI Yiyang
The Fourth Affiliated Hospital,Zhejiang University School of Medicine,Zhejiang Jinhua 322000,China.
Keywords:
gastric cancercolorectal cancerliquid biopsycirculating tumor DNAdiagnosis
PACS:
R735
DOI:
10.3969/j.issn.1672-4992.2024.15.034
Abstract:
Cancer threatens human health.Gastric cancer(GC) and colorectal cancer(CRC) are the leading causes of cancer-related deaths worldwide.Early diagnosis is particularly important for improving the survival rate of GC and CRC,but the current clinical screening methods have certain limitations.Recently,liquid biopsy has received extensive attention from researchers.Circulating tumor DNA(ctDNA) is the free DNA fragment derived from tumors in body fluids,which carries tumor-related genetic information.Relevant studies have shown that ctDNA detection may be used in the early diagnosis of GC and CRC.This article mainly reviews what is ctDNA and its application progress in the early diagnosis.

References:

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Last Update: 2024-06-28